Journal:Acta Cryst F:S2053230X19004618

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<scene name='81/813404/Cv/2'>Asymmetric unit contains 6 protomers that form a dimer of trimers</scene> ([[5v68]]). Protomers A and C shown in blue, protomer B shown in gray, protomers D and F shown in red, protomer E shown in cyan, GDP are represented by orange spheres, and PO4 by green spheres. <scene name='81/813404/Cv/4'>Trimer ABC superimposed onto DEF</scene>. Same color scheme as in previous scene.
<scene name='81/813404/Cv/2'>Asymmetric unit contains 6 protomers that form a dimer of trimers</scene> ([[5v68]]). Protomers A and C shown in blue, protomer B shown in gray, protomers D and F shown in red, protomer E shown in cyan, GDP are represented by orange spheres, and PO4 by green spheres. <scene name='81/813404/Cv/4'>Trimer ABC superimposed onto DEF</scene>. Same color scheme as in previous scene.
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Comparison of other MtbFtsZ structures with trimer ABC from [[5v68]] reveals that protomers A and B superimposed well but the conformation of protomer C is vastly different. <scene name='81/813404/Cv/6'>Structure 5V68 superimposed onto 4KWE</scene>. Nucleotide for both is GDP.trimer ABC from [[5v68]] is to a curved MtbFtsZ protofilament (PDB [[4kwe]]). Based on an r.m.s.d. of 1.2Å between protomers AB of [[5v68]] and protomers CB of [[4kwe]], protomers A and B from [[5v68]] are similar with protomers C and B of [[4kwe]]. Glu231 (shown as green spheres) from protomer C from [[5v68]] and Glu231 from protomer A of [[4kwe]] are far apart with a distance of 53.8Å.
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Comparison of other MtbFtsZ structures with trimer ABC from [[5v68]] reveals that protomers A and B superimposed well but the conformation of protomer C is vastly different. <scene name='81/813404/Cv/6'>Structure 5V68 superimposed onto 4KWE</scene>. Nucleotide for both is GDP. Color scheme is as follows, [[5v68]] blue, [[4kwe]] yellow, nucleotides orange spheres, Glu231 green spheres, phosphate red spheres. The trimer ABC from [[5v68]] is to a curved MtbFtsZ protofilament (PDB [[4kwe]]). Based on an r.m.s.d. of 1.2Å between protomers AB of [[5v68]] and protomers CB of [[4kwe]], protomers A and B from [[5v68]] are similar with protomers C and B of [[4kwe]]. Glu231 (shown as green spheres) from protomer C from [[5v68]] and Glu231 from protomer A of [[4kwe]] are far apart with a distance of 53.8Å.
<b>References</b><br>
<b>References</b><br>

Revision as of 13:30, 15 April 2019

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