Journal:Acta Cryst F:S2053230X19004618
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<scene name='81/813404/Cv/2'>Asymmetric unit contains 6 protomers that form a dimer of trimers</scene> ([[5v68]]). Protomers A and C shown in blue, protomer B shown in gray, protomers D and F shown in red, protomer E shown in cyan, GDP are represented by orange spheres, and PO4 by green spheres. <scene name='81/813404/Cv/4'>Trimer ABC superimposed onto DEF</scene>. Same color scheme as in previous scene. | <scene name='81/813404/Cv/2'>Asymmetric unit contains 6 protomers that form a dimer of trimers</scene> ([[5v68]]). Protomers A and C shown in blue, protomer B shown in gray, protomers D and F shown in red, protomer E shown in cyan, GDP are represented by orange spheres, and PO4 by green spheres. <scene name='81/813404/Cv/4'>Trimer ABC superimposed onto DEF</scene>. Same color scheme as in previous scene. | ||
| - | Comparison of other MtbFtsZ structures with trimer ABC from [[5v68]] reveals that protomers A and B superimposed well but the conformation of protomer C is vastly different. <scene name='81/813404/Cv/10'>Structure 5V68 superimposed onto 4KWE</scene>. Nucleotide for both is GDP. Color scheme is as follows, [[5v68]] blue, [[4kwe]] yellow, nucleotides orange spheres, Glu231 green spheres, phosphate red spheres. <scene name='81/813404/Cv/9'>Click here to see animation of this scene</scene>. The trimer ABC from [[5v68]] is to a curved MtbFtsZ protofilament (PDB [[4kwe]]). Based on an r.m.s.d. of 1.2Å between protomers AB of [[5v68]] and protomers CB of [[4kwe]], protomers A and B from [[5v68]] are similar with protomers C and B of [[4kwe]]. <scene name='81/813404/Cv/11'>Glu231 (shown as green sphere) from protomer C of [[5v68]] and Glu231 from protomer A of [[4kwe]] are far apart</scene>. | + | Comparison of other MtbFtsZ structures with trimer ABC from [[5v68]] reveals that protomers A and B superimposed well but the conformation of protomer C is vastly different. <scene name='81/813404/Cv/10'>Structure 5V68 superimposed onto 4KWE</scene>. Nucleotide for both is GDP. Color scheme is as follows, [[5v68]] blue, [[4kwe]] yellow, nucleotides orange spheres, Glu231 green spheres, phosphate red spheres. <scene name='81/813404/Cv/9'>Click here to see animation of this scene</scene>. <jmol><jmolButton> |
| + | <script>if (_animating); anim pause;set echo bottom left; color echo white; font echo 20 sansserif;echo Animation Paused; else; anim resume; set echo off;endif;</script> | ||
| + | <text>Toggle Animation</text> | ||
| + | </jmolButton></jmol> The trimer ABC from [[5v68]] is to a curved MtbFtsZ protofilament (PDB [[4kwe]]). Based on an r.m.s.d. of 1.2Å between protomers AB of [[5v68]] and protomers CB of [[4kwe]], protomers A and B from [[5v68]] are similar with protomers C and B of [[4kwe]]. <scene name='81/813404/Cv/11'>Glu231 (shown as green sphere) from protomer C of [[5v68]] and Glu231 from protomer A of [[4kwe]] are far apart</scene>. | ||
<b>References</b><br> | <b>References</b><br> | ||
Revision as of 12:25, 16 April 2019
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This page complements a publication in scientific journals and is one of the Proteopedia's Interactive 3D Complement pages. For aditional details please see I3DC.
