Carbonyl reductase

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==3D structures of carbonyl reductase==
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
 
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*Carbonyl reductase
 
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**[[1zze]] – CBR – ''Sporidiobolus salmonicolor''<BR />
 
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**[[3afm]] – SpCBR – ''Sphingomonas''<br />
 
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**[[4w7h]] – SpCBR (mutant)<br />
 
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**[[5gmo]] – CBR – ''Scheffersomyces spiritis''<br />
 
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**[[5tqv]] – BmCBR – ''Burkholderia multivorans''<br />
 
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*(R)-specific carbonyl reductase
 
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**[[3ctm]], [[4oaq]] – CpCBR – ''Candida parapsilosis''<br />
 
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**[[4oaq]] – CpCBR + Zn<br />
 
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**[[3wle]], [[4c4o]] – CpCBR + NAD + Zn<br />
 
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**[[3wlf]] – CpCBR + phenylethane diol + Zn<br />
 
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**[[3wnq]] – CpCBR (mutant) + hydroxyacetophenone + Zn<br />
 
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*Carbonyl reductase binary complex with NADPH
 
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**[[3bhi]] - hCBR1 + NADPH - human<BR />
 
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**[[2hrb]] – hCBR3 + NADPH<BR />
 
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**[[3afn]] – SpCBR + NADP<br />
 
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**[[5u1p]] – BmCBR + NADP <br />
 
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*Carbonyl reductase ternary complex with NADPH
 
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**[[1cyd]] – CBR + 2-propanol + NADPH – mouse<BR />
 
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**[[1wma]] – hCBR1 + hydroxyl-PP + NADPH<BR />
 
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**[[2pfg]] - hCBR1 + bicycle-undecane + NADPH<BR />
 
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**[[3bhj]], [[4z3d]] - hCBR1 + glutathione + NADPH<BR />
 
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**[[3bhm]] - hCBR1 + hydroxymethylglutathione + NADPH<BR />
 
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**[[4cql]] – hCBR + estradiol dehydrogenase + NAD<br />
 
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**[[4cqm]] – hCBR + estradiol dehydrogenase + NAD + NADP<br />
 
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}}
 
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 08:12, 23 April 2019

Mouse carbonyl reductase tetramer complex with 2-propanol and NADPH, 1cyd

Drag the structure with the mouse to rotate

References

  1. Forrest GL, Gonzalez B. Carbonyl reductase. Chem Biol Interact. 2000 Dec 1;129(1-2):21-40. PMID:11154733
  2. Tanaka N, Nonaka T, Nakanishi M, Deyashiki Y, Hara A, Mitsui Y. Crystal structure of the ternary complex of mouse lung carbonyl reductase at 1.8 A resolution: the structural origin of coenzyme specificity in the short-chain dehydrogenase/reductase family. Structure. 1996 Jan 15;4(1):33-45. PMID:8805511

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Michal Harel, Alexander Berchansky

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