Journal:IUCrJ:S2052252519005761

Room-temperature photo-induced martensitic transformation in a protein crystal

Steven Dajnowicz, Patricia S. Langan, Kevin L. Weiss, Ilia N. Ivanov, and Andrey Kovalevsky ^[1]

Molecular Tour
Martensitic transformations are the first-order crystal-to-crystal phase transitions that occur mostly in materials such as steel, alloys and ceramics, but are rare in molecular crystals and have not been detected in protein crystals. We discovered that crystals of a reversibly switchable fluorescent protein Tetdron can undergo the martensitic transformation by illumination with 400 nm light at room temperature. The phase transition results in the protein in crystallo tetramerization coupled to the chromophore deprotonation and substantial changes in the crystal packing as demonstrated by X-ray photocrystallography and spectroscopic measurements. The remarkable property of Tetdron crystals to undergo the photo-induced martensitic transformation can be explored to create novel martensitic biomaterials such as biomachines for biomedical applications, in which a protein molecule would play a role of a tiny molecular nanomachine to produce work. Tetdron may also find applications in future data storage devices with extreme capacities since 1 petabits of data can theoretically be written inside a Tetdron crystal measuring only 1 mm on a side.

References

1. ↑ Dajnowicz S, Langan PS, Weiss KL, Ivanov IN, Kovalevsky A. Room-temperature photo-induced martensitic transformation in a protein crystal. IUCrJ. 2019 May 22;6(Pt 4):619-629. doi: 10.1107/S2052252519005761. eCollection, 2019 Jul 1. PMID:31316806 doi:http://dx.doi.org/10.1107/S2052252519005761