Catenin
From Proteopedia
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| - | + | <StructureSection load='2z6g' size='350' side='right' scene='41/417478/Cv/3' caption='Zebrafish β-catenin (PDB code [[2z6g]])'> | |
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| + | == Function == | ||
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| + | [[Catenin|Catenins]] (CTN) are proteins which make complexes with [[cadherin]].<ref>PMID:17005550</ref><br /> | ||
| + | * '''α-CTN''' links cadherin (CDH) and α-actinin, it is encoded by 3 genes: '''α-E-CTN''' (epithelial), '''α-T-CTN''' (membrane bound), and '''α-N-CTN''' (neuronal).<br /> | ||
| + | * '''β-CTN''' is a subunit of the cadherin complex. It contains [[Armadillo repeats]] which are a pair of helices forming hairpin structure.<br /> | ||
| + | * '''γ-CTN''' (or '''plakoglobin''') is a component of desmosomes and contains armadillo repeats.<br /> | ||
| + | * '''δ-CTN''' is expressed in the brain and contains 10 armadillo repeats.<br /> | ||
| + | * '''p120 CTN''' is another member of the CTN family.<br /> | ||
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| + | == 3D Structures of Catenin == | ||
| + | [[Catenin 3D structures]] | ||
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| + | </StructureSection> | ||
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| + | == References == | ||
| + | <references/> | ||
| + | [[Category:Topic Page]] | ||
Current revision
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References
- ↑ Weis WI, Nelson WJ. Re-solving the cadherin-catenin-actin conundrum. J Biol Chem. 2006 Nov 24;281(47):35593-7. Epub 2006 Sep 27. PMID:17005550 doi:http://dx.doi.org/10.1074/jbc.R600027200
