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Concanavalin
From Proteopedia
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== Function == | == Function == | ||
| - | '''Concanavalin A''' (ConA) is a carbohydrate-binding protein from jack-bean (''Canavalia ensiformis''). It binds to certain sugars and to metal. It is used to characterize glycoproteins on cell surfaces.<ref>PMID:9546043</ref> | + | '''Concanavalin A''' (ConA) is a carbohydrate-binding protein from jack-bean (''Canavalia ensiformis''). It binds to certain sugars and to metal. It is used to characterize glycoproteins on cell surfaces.<ref>PMID:9546043</ref>. '''Concanavalin B''' (ConB) is related to chitinase with 40% sequence identity.<ref>PMID:7490746</ref>. '''Concanavalin V''' (ConV) is a D-mannose/D-glucose-binding lectin. |
== Relevance == | == Relevance == | ||
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</StructureSection> | </StructureSection> | ||
| - | == 3D Structures of Concanavalin A == | ||
| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | |||
| - | *Concanavalin A | ||
| - | |||
| - | **[[2uu8]], [[1nxd]], [[1gkb]], [[3enr]], [[1qny]], [[1vln]], [[1jbc]], [[1cnv]], [[2cna]], [[3cna]], [[3nwk]], [[5o6n]], [[6caf]],[[5z5l]], [[5z5n]], [[5z5p]], [[5z5y]], [[5zac]], [[6ahg]], [[6h2m]] – CeConA – ''Canavalia ensiformis''<br /> | ||
| - | **[[2yz4]], [[1xqn]], [[1c57]] – CeConA – neutron<br /> | ||
| - | **[[2ctv]] – CeConA – Laue<br /> | ||
| - | **[[1cn1]], [[1apn]], [[1dq0]], [[1dq2]] – CeConA demetallized<br /> | ||
| - | **[[5ygm]] – CeConA (mutant)<br /> | ||
| - | **[[2g4i]], [[2a7a]] – ConA – ''Canavalia virosa''<br /> | ||
| - | **[[1wuv]] – CgConA – ''Canavalia gladiata''<br /> | ||
| - | **[[3ju9]], [[1azd]] – BrConBR – Brazilian jack-bean<br /> | ||
| - | **[[2cwm]] - CmConA – ''Canavalia maritima''<br /> | ||
| - | **[[5byn]] – ClConA – ''Canavalia lineata''<br /> | ||
| - | |||
| - | *Concanavalin A binary complex | ||
| - | |||
| - | **[[1dq1]], [[1dq5]], [[1dq6]], [[1qgl]], [[1nls]], [[1scr]], [[1scs]] – CeConA + ion<br /> | ||
| - | **[[1enq]], [[1enr]], [[1ens]], [[1con]], [[1dq4]], [[2enr]], [[1ces]] - CeConA demetallized + ion<br /> | ||
| - | **[[3d4k]] – CeConA + sugar analog<br /> | ||
| - | **[[1hqw]], [[1jyc]], [[1jyi]], [[1jui]], [[1joj]], [[1jw6]] – CeConA + polypeptide<br /> | ||
| - | **[[1jn2]] – CeConA + porphyrin derivative<br /> | ||
| - | **[[1cjp]], [[1ona]], [[1gic]], [[1val]], [[1vam]], [[5cna]], [[4p9x]], [[4p9w]], [[4p9y]], [[4pf5]] – CeConA + pyranoside derivative<br /> | ||
| - | **[[1i3h]], [[1qdc]], [[1qdo]], [[1bxh]], [[1tei]], [[1cvn]] – CeConA + glucoside<br /> | ||
| - | **[[5wey]] – CeConA + mannobiose<br /> | ||
| - | **[[2p37]], [[2cy6]], [[2cyf]], [[2ow4]], [[2p34]] – CmConA + glucoside <br /> | ||
| - | **[[2ef6]], [[2d7f]], [[2ovu]], [[2p2k]] - CgConA + glucoside<br /> | ||
| - | **[[3qlq]] - CcConA + glucosyl-octasilsesquioxane – ''Canavalia cathartica''<br /> | ||
| - | **[[4czs]] – CcConA + mannose peptide<br /> | ||
| - | **[[5f5q]] – CcConA + mannoside<br /> | ||
| - | **[[4p14]] – CbConA + adenine – ''Canavalia brasiliensis''<br /> | ||
| - | **[[4pcr]] – CbConA + GABA<br /> | ||
| - | **[[3snm]] - ClConA + indole-acetate <br /> | ||
| - | **[[4i30]], [[4tys]] – ClConA + nucleotide<br /> | ||
| - | **[[4tzd]] – ClConA + DNA<br /> | ||
| - | **[[4h55]] - BrConA + glucoside<br /> | ||
| - | **[[4dpn]] – ClConA + resveratrol<br /> | ||
| - | |||
| - | *Concanavalin B | ||
| - | |||
| - | **[[6gwa]] – CeConB – electron laser<br /> | ||
| - | |||
| - | *Concanavalin V | ||
| - | |||
| - | **[[6gw9]] – CeConV – electron laser<br /> | ||
| - | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
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References
- ↑ Loris R, Hamelryck T, Bouckaert J, Wyns L. Legume lectin structure. Biochim Biophys Acta. 1998 Mar 3;1383(1):9-36. PMID:9546043
- ↑ Hennig M, Jansonius JN, Terwisscha van Scheltinga AC, Dijkstra BW, Schlesier B. Crystal structure of concanavalin B at 1.65 A resolution. An "inactivated" chitinase from seeds of Canavalia ensiformis. J Mol Biol. 1995 Nov 24;254(2):237-46. PMID:7490746 doi:http://dx.doi.org/10.1006/jmbi.1995.0614
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