This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4x37
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | |||
==Gallus interleukin-1 mutant - E118K== | ==Gallus interleukin-1 mutant - E118K== | ||
| - | <StructureSection load='4x37' size='340' side='right' caption='[[4x37]], [[Resolution|resolution]] 1.63Å' scene=''> | + | <StructureSection load='4x37' size='340' side='right'caption='[[4x37]], [[Resolution|resolution]] 1.63Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4x37]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X37 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X37 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4x37]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X37 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X37 FirstGlance]. <br> |
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4x38|4x38]], [[4x39|4x39]], [[4x3a|4x3a]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4x38|4x38]], [[4x39|4x39]], [[4x3a|4x3a]]</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x37 OCA], [http://pdbe.org/4x37 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x37 RCSB], [http://www.ebi.ac.uk/pdbsum/4x37 PDBsum]</span></td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">il-1beta, IL1B, IL1beta ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x37 OCA], [http://pdbe.org/4x37 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x37 RCSB], [http://www.ebi.ac.uk/pdbsum/4x37 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4x37 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/O73909_CHICK O73909_CHICK]] Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).[RuleBase:RU003753] | [[http://www.uniprot.org/uniprot/O73909_CHICK O73909_CHICK]] Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).[RuleBase:RU003753] | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Interleukin|Interleukin]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Chick]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Cheng, T]] | [[Category: Cheng, T]] | ||
[[Category: Cheng, W T]] | [[Category: Cheng, W T]] | ||
[[Category: Yin, H S]] | [[Category: Yin, H S]] | ||
[[Category: Immune system]] | [[Category: Immune system]] | ||
Revision as of 06:58, 29 May 2019
Gallus interleukin-1 mutant - E118K
| |||||||||||
