This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4xmw
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | |||
==Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-aspartic acid== | ==Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-aspartic acid== | ||
| - | <StructureSection load='4xmw' size='340' side='right' caption='[[4xmw]], [[Resolution|resolution]] 2.20Å' scene=''> | + | <StructureSection load='4xmw' size='340' side='right'caption='[[4xmw]], [[Resolution|resolution]] 2.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4xmw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XMW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XMW FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4xmw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XMW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XMW FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ASP:ASPARTIC+ACID'>ASP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ASP:ASPARTIC+ACID'>ASP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4xms|4xms]], [[4xmt|4xmt]], [[4xmu|4xmu]], [[4xmv|4xmv]], [[4xmx|4xmx]], [[4xmz|4xmz]], [[4xn1|4xn1]], [[4xn2|4xn2]], [[4xn4|4xn4]], [[4xn5|4xn5]], [[4xn7|4xn7]], [[4xn8|4xn8]], [[4xn9|4xn9]], [[4xna|4xna]], [[4xnb|4xnb]], [[4xnd|4xnd]], [[4xo3|4xo3]], [[4xo4|4xo4]], [[4xo5|4xo5]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4xms|4xms]], [[4xmt|4xmt]], [[4xmu|4xmu]], [[4xmv|4xmv]], [[4xmx|4xmx]], [[4xmz|4xmz]], [[4xn1|4xn1]], [[4xn2|4xn2]], [[4xn4|4xn4]], [[4xn5|4xn5]], [[4xn7|4xn7]], [[4xn8|4xn8]], [[4xn9|4xn9]], [[4xna|4xna]], [[4xnb|4xnb]], [[4xnd|4xnd]], [[4xo3|4xo3]], [[4xo4|4xo4]], [[4xo5|4xo5]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pepN, b0932, JW0915 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Membrane_alanyl_aminopeptidase Membrane alanyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.2 3.4.11.2] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Membrane_alanyl_aminopeptidase Membrane alanyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.2 3.4.11.2] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xmw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xmw OCA], [http://pdbe.org/4xmw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xmw RCSB], [http://www.ebi.ac.uk/pdbsum/4xmw PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xmw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xmw OCA], [http://pdbe.org/4xmw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xmw RCSB], [http://www.ebi.ac.uk/pdbsum/4xmw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xmw ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/AMPN_ECOLI AMPN_ECOLI]] Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation. | [[http://www.uniprot.org/uniprot/AMPN_ECOLI AMPN_ECOLI]] Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation. | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Ecoli]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Membrane alanyl aminopeptidase]] | [[Category: Membrane alanyl aminopeptidase]] | ||
[[Category: Addlagatta, A]] | [[Category: Addlagatta, A]] | ||
Revision as of 07:34, 29 May 2019
Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-aspartic acid
| |||||||||||
