Defensin

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DEF contains <scene name='50/509378/Cv/5'>6-8 conserved cysteine residues</scene>.
DEF contains <scene name='50/509378/Cv/5'>6-8 conserved cysteine residues</scene>.
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==3D structures of defensin==
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[[Defensin 3D structures]]
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</StructureSection>
</StructureSection>
==3D structures of defensin==
==3D structures of defensin==
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**[[1kj6]] – hDEFB3 – NMR<BR />
**[[1kj6]] – hDEFB3 – NMR<BR />
**[[5ki9]] – hDEFB4<br />
**[[5ki9]] – hDEFB4<br />
 +
**[[6cs9]] – hDEFB4A + PIP2<br />
**[[1e4t]] – mDEFB7 – NMR<BR />
**[[1e4t]] – mDEFB7 – NMR<BR />
**[[1e4r]] - mDEFB8 – NMR<BR />
**[[1e4r]] - mDEFB8 – NMR<BR />
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**[[3lo9]] – hDEF1 (mutant)<br />
**[[3lo9]] – hDEF1 (mutant)<br />
**[[5nce]] – DEF1 – pine - NMR<br />
**[[5nce]] – DEF1 – pine - NMR<br />
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**[[6b9w]], [[6bam]], [[6bb6]], [[6bi5]] – DEF1 – mexican scorpion - NMR<br />
*Defensin-2
*Defensin-2
**[[2gl1]] – VrDEF2 - ''Vigna radiata''<br />
**[[2gl1]] – VrDEF2 - ''Vigna radiata''<br />
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*Defensin-4
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**[[6dmm]], [[6dmq]] – hDEF4 (mutant)<br />
*Defensin-5
*Defensin-5
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**[[2lj7]] – DEF – lentil – NMR<br />
**[[2lj7]] – DEF – lentil – NMR<br />
**[[2lr3]] – DEF – barrel medic – NMR<br />
**[[2lr3]] – DEF – barrel medic – NMR<br />
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**[[6mry]] - DEF NOD173 – ''Nicotiana occidentalis''<br />
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**[[6b55]] - DEF – ''Nicotiana alata''<br />
}}
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 10:09, 4 June 2019

Human α-defensin 1 (PDB entry 2pm4)

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3D structures of defensin

Updated on 04-June-2019


References

  1. White SH, Wimley WC, Selsted ME. Structure, function, and membrane integration of defensins. Curr Opin Struct Biol. 1995 Aug;5(4):521-7. PMID:8528769
  2. Ganz T, Selsted ME, Szklarek D, Harwig SS, Daher K, Bainton DF, Lehrer RI. Defensins. Natural peptide antibiotics of human neutrophils. J Clin Invest. 1985 Oct;76(4):1427-35. PMID:2997278 doi:http://dx.doi.org/10.1172/JCI112120
  3. Zhuravel OV, Gerashchenko OL, Khetsuriani MR, Soldatkina MA, Pogrebnoy PV. Expression of human beta-defensins-1-4 in thyroid cancer cells and new insight on biologic activity of hBD-2 in vitro. Exp Oncol. 2014 Sep;36(3):174-8. PMID:25265350

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Michal Harel, Alexander Berchansky

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