Dehaloperoxidase

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{{STRUCTURE_1ewa| PDB=1ewa | SIZE=400| SCENE= |right|CAPTION=Dehaloperoxidase heme-containing dimer complex with iodophenol and sulfate ions, [[1ewa]] }}
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<StructureSection load='4fh6' size='350' side='right' caption='Dehaloperoxidase heme-containing dimer complex with tribromophenol, O2 and sulfate ions (PDB entry [[4fh6]])' scene='48/484818/Cv/1'>
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'''Dehaloperoxidase''' (DHP) is a heme-containing globin possessing peroxidase enzymatic activity. DHP catalyzes the peroxide-dependent dehalogenation of halophenol. DHP A and DHP B are isoenzymes of DHP.<ref>PMID:24791647</ref>
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'''Dehaloperoxidase''' (DHP) is a heme-containing globin possessing peroxidase enzymatic activity. DHP catalyzes the peroxide-dependent dehalogenation of halophenol. DHP A and DHP B are isoenzymes of DHP.
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==3D structures of dehalperoxidase==
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== Structural highlights ==
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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<scene name='48/484818/Cv/3'>Tribromophenol and an O2 molecule are seen in the heme-containing active site</scene>. <ref>PMID:23480178</ref>
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[[1ew6]] – AoDHP – ''Amphitrite ornate''<br />
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==3D structures of dehaloperoxidase==
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[[2qfk]], [[3dr9]], [[3kun]], [[3kuo]], [[3lb1]], [[3lb2]], [[3lb3]], [[3lb4]], [[3mou]], [[3ord]] – AoDHP A<br />
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[[Dehaloperoxidase 3D structures]]
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[[2qfn]], [[3k3u]], [[3mym]], [[3myn]], [[3o7n]], [[3oj1]] – AoDHP A (mutant) <br />
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[[3ixf]] – AoDHP B
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'''DHP complex with halophenol'''
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</StructureSection>
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[[1ewa]] – AoDHP + iodophenol<br />
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[[3ok5]] - AoDHP A (mutant) + bromophenol
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== References ==
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<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Dehaloperoxidase heme-containing dimer complex with tribromophenol, O2 and sulfate ions (PDB entry 4fh6)

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References

  1. ↑ Barrios DA, D'Antonio J, McCombs NL, Zhao J, Franzen S, Schmidt AC, Sombers LA, Ghiladi RA. Peroxygenase and oxidase activities of dehaloperoxidase-hemoglobin from Amphitrite ornata. J Am Chem Soc. 2014 Jun 4;136(22):7914-25. doi: 10.1021/ja500293c. Epub 2014 May , 21. PMID:24791647 doi:http://dx.doi.org/10.1021/ja500293c
  2. ↑ Zhao J, de Serrano VS, Zhao J, Le PD, Franzen S. Structural and kinetic study of an internal substrate binding site of dehaloperoxidase-hemoglobin A from Amphitrite ornata. Biochemistry. 2013 Mar 12. PMID:23480178 doi:http://dx.doi.org/10.1021/bi301307f

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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