This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4y20
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Complex of human Galectin-1 and NeuAcalpha2-3Galbeta1-4Glc== | ==Complex of human Galectin-1 and NeuAcalpha2-3Galbeta1-4Glc== | ||
| - | <StructureSection load='4y20' size='340' side='right' caption='[[4y20]], [[Resolution|resolution]] 2.20Å' scene=''> | + | <StructureSection load='4y20' size='340' side='right'caption='[[4y20]], [[Resolution|resolution]] 2.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4y20]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y20 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y20 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4y20]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y20 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y20 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SLT:5-(ACETYLAMINO)-3,5-DIDEOXYNON-2-ULOPYRANONOSYL-(2- 3)-BETA-D-LYXO-HEXOPYRANOSYL-(1- 4)HEXOPYRANOSE'>SLT</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SLT:5-(ACETYLAMINO)-3,5-DIDEOXYNON-2-ULOPYRANONOSYL-(2- 3)-BETA-D-LYXO-HEXOPYRANOSYL-(1- 4)HEXOPYRANOSE'>SLT</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4y1v|4y1v]], [[4y1u|4y1u]], [[4y1x|4y1x]], [[4y1y|4y1y]], [[4y1z|4y1z]], [[4y22|4y22]], [[4y24|4y24]], [[4y26|4y26]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4y1v|4y1v]], [[4y1u|4y1u]], [[4y1x|4y1x]], [[4y1y|4y1y]], [[4y1z|4y1z]], [[4y22|4y22]], [[4y24|4y24]], [[4y26|4y26]]</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y20 OCA], [http://pdbe.org/4y20 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y20 RCSB], [http://www.ebi.ac.uk/pdbsum/4y20 PDBsum]</span></td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LGALS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y20 OCA], [http://pdbe.org/4y20 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y20 RCSB], [http://www.ebi.ac.uk/pdbsum/4y20 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4y20 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/LEG1_HUMAN LEG1_HUMAN]] May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.<ref>PMID:14617626</ref> <ref>PMID:18796645</ref> | [[http://www.uniprot.org/uniprot/LEG1_HUMAN LEG1_HUMAN]] May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.<ref>PMID:14617626</ref> <ref>PMID:18796645</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Galectin|Galectin]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Hsieh, T J]] | [[Category: Hsieh, T J]] | ||
[[Category: Lin, C H]] | [[Category: Lin, C H]] | ||
Revision as of 23:48, 5 June 2019
Complex of human Galectin-1 and NeuAcalpha2-3Galbeta1-4Glc
| |||||||||||
