DNA glycosylase
From Proteopedia
(Difference between revisions)
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**[[3a7n]], [[4wpk]], [[4wrw]], [[4wrx]] – MtUDG – ''Mycobacterium tuberculosis''<BR /> | **[[3a7n]], [[4wpk]], [[4wrw]], [[4wrx]] – MtUDG – ''Mycobacterium tuberculosis''<BR /> | ||
| + | **[[6ajs]] – MsUDG – ''Mycobacterium smegmatis''<br /> | ||
| + | **[[6ajq]] – MsUDG (mutant)<br /> | ||
| + | **[[6ail]] – MsUDG X<br /> | ||
**[[3tr7]] – UDG – ''Coxiella burnetii''<br /> | **[[3tr7]] – UDG – ''Coxiella burnetii''<br /> | ||
**[[1akz]], [[3tkb]], [[1yuo]] - hUDG (mutant) <BR /> | **[[1akz]], [[3tkb]], [[1yuo]] - hUDG (mutant) <BR /> | ||
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**[[2ddg]], [[2dem]], [[2dp6]] – TtUDG + DNA + deoxyphosphono ribose<br /> | **[[2ddg]], [[2dem]], [[2dp6]] – TtUDG + DNA + deoxyphosphono ribose<br /> | ||
**[[5nnu]] – HhUDG + DNA <br /> | **[[5nnu]] – HhUDG + DNA <br /> | ||
| + | **[[6ajo]] – MsUDG + DNA<br /> | ||
*Uracil-DNA glycosylase complex with uracil derivatives | *Uracil-DNA glycosylase complex with uracil derivatives | ||
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**[[4wpl]], [[4wru]], [[4wrv]] – MtUDG + uracil<br /> | **[[4wpl]], [[4wru]], [[4wrv]] – MtUDG + uracil<br /> | ||
**[[4wry]], [[4wrz]], [[4ws0]], [[4ws1]], [[4ws2]], [[4ws3]], [[4ws4]], [[4ws5]], [[4ws6]], [[4ws7]], [[4ws8]] – MtUDG + uracil derivative<br /> | **[[4wry]], [[4wrz]], [[4ws0]], [[4ws1]], [[4ws2]], [[4ws3]], [[4ws4]], [[4ws5]], [[4ws6]], [[4ws7]], [[4ws8]] – MtUDG + uracil derivative<br /> | ||
| + | **[[6ajr]] – MsUDG + uracil<br /> | ||
| + | **[[6ajp]] – MsUDG + deoxy-UMP <br /> | ||
**[[2d3y]] – TtUDG + Fe4S4 + deoxy-UMP <br /> | **[[2d3y]] – TtUDG + Fe4S4 + deoxy-UMP <br /> | ||
**[[2c53]] – HsvUDG (mutant) + deoxyuridine<br /> | **[[2c53]] – HsvUDG (mutant) + deoxyuridine<br /> | ||
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*Human 8-oxoguanine DG | *Human 8-oxoguanine DG | ||
| - | **[[1ko9]] – hOgg1<BR /> | + | **[[1ko9]], [[5an4]] – hOgg1<BR /> |
**[[2xhi]], [[3ktu]], [[1hu0]], [[1fn7]] - hOgg1 + DNA<BR /> | **[[2xhi]], [[3ktu]], [[1hu0]], [[1fn7]] - hOgg1 + DNA<BR /> | ||
**[[1lwv]], [[1lww]], [[1lwy]] - hOgg1 + DNA<BR /> + guanine derivative<BR /> | **[[1lwv]], [[1lww]], [[1lwy]] - hOgg1 + DNA<BR /> + guanine derivative<BR /> | ||
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*8-oxoguanine (oxoG) DG | *8-oxoguanine (oxoG) DG | ||
| + | **[[6g3x]] – mOgg1 – mouse<br /> | ||
| + | **[[6g40]], [[6g3y]] – mOgg1 + inhibitor<br /> | ||
**[[3n0u]] – TmOxDG<BR /> | **[[3n0u]] – TmOxDG<BR /> | ||
**[[3knt]] - MjOxDG (mutant) + DNA – ''Methanocaldococcus jannaschii''<BR /> | **[[3knt]] - MjOxDG (mutant) + DNA – ''Methanocaldococcus jannaschii''<BR /> | ||
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**[[1xqo]], [[1xqp]] – OxDG – ''Pyrobaculum aerophilum''<br /> | **[[1xqo]], [[1xqp]] – OxDG – ''Pyrobaculum aerophilum''<br /> | ||
**[[4ejy]], [[4ejz]] – OxDG + DNA – ''Thermoanaerobacter tengcongensis''<br /> | **[[4ejy]], [[4ejz]] – OxDG + DNA – ''Thermoanaerobacter tengcongensis''<br /> | ||
| + | **[[4pii]] – OxDG – ''Pyrococcus furiosus''<br /> | ||
*Methyladenine DG | *Methyladenine DG | ||
Revision as of 07:04, 12 June 2019
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3D Structures of DNA glycosylase
Updated on 12-June-2019
References
- ↑ Fromme JC, Banerjee A, Verdine GL. DNA glycosylase recognition and catalysis. Curr Opin Struct Biol. 2004 Feb;14(1):43-9. PMID:15102448 doi:http://dx.doi.org/10.1016/j.sbi.2004.01.003
- ↑ Willetts KE, Rey F, Agostini I, Navarro JM, Baudat Y, Vigne R, Sire J. DNA repair enzyme uracil DNA glycosylase is specifically incorporated into human immunodeficiency virus type 1 viral particles through a Vpr-independent mechanism. J Virol. 1999 Feb;73(2):1682-8. PMID:9882380
- ↑ Fromme JC, Banerjee A, Huang SJ, Verdine GL. Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase. Nature. 2004 Feb 12;427(6975):652-6. PMID:14961129 doi:10.1038/nature02306
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Michal Harel, Alexander Berchansky, Joel L. Sussman, Jaime Prilusky
