Enoylpyruvate transferase

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</StructureSection>
</StructureSection>
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== 3D Structures of enoylpyruvate transferase ==
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
 
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*MurA
 
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**[[1naw]], [[1ejc]], [[1ejd]] – EncMurA – ''Enterobacter cloacae''<BR />
 
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**[[1dlg]], [[3spb]], [[3v5v]], [[4e7g]], [[4eii]] – EncMurA (mutant) <BR />
 
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**[[1uae]] – EcMurA – ''Escherichia coli''<BR />
 
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**[[2yvw]] – AaMurA – ''Aquifex aeolicus''<BR />
 
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**[[3zh3]], [[3zh4]] – SpMurA – ''Streptococcus pneumoniae''<BR />
 
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**[[3r38]] – MurA – ''Listeria monocytogenes''<br />
 
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**[[3sg1]] – MurA – ''Bacillus anthracis''<br />
 
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**[[5ujs]] – MurA – ''Campylobacter jejuni''<BR />
 
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*MurA binary complex
 
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**[[1a2n]] – EcMurA (mutant) + reaction intermediate<BR />
 
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**[[3iss]] – EcMurA (mutant) + enoylpyruvyl-UNAG <BR />
 
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**[[1eyn]] – EncMurA (mutant) + aniline-naphthalene sulfonate<BR />
 
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**[[4e7b]] – EncMurA + UDP-glucose<BR />
 
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**[[4e7e]] – EncMurA (mutant) + UDP-glucose<BR />
 
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**[[4e7c]] – EncMurA + UTP<BR />
 
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**[[4e7d]] – EncMurA + UDP<BR />
 
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**[[4e7f]] – EncMurA (mutant) + UDP<BR />
 
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**[[1q3g]] – EncMurA (mutant) + reaction intermediate<BR />
 
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**[[2rl1]] – HiMurA + UNAG – Haemophilus influenzae<BR />
 
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**[[3kqj]] – EcMurA + UNAG <BR />
 
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**[[5vm7]] – EcMurA + maturation protein A2 <BR />
 
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**[[3upk]] – EncMurA + UNAG <BR />
 
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**[[1ybg]] – EcMurA (mutant) + inhibitor<BR />
 
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**[[3kqa]] – EncMurA + terreic acid inhibitor<BR />
 
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**[[3swq]] – EncMurA (mutant) + enoylpyruvyl-UNAG <BR />
 
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**[[3v4t]], [[1ryw]] – EncMurA (mutant) + UNAG <BR />
 
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**[[5u4h]] – MurA + phosphonooxy propanoate – ''Acinetobacter baumannii''<BR />
 
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**[[6nkj]] – SpMurA + phosphonooxy propanoate <BR />
 
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**[[5bq2]] – MurA + enoylpyruvyl-UNAG – ''Pseudomonas aeruginosa''<BR />
 
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*MurA ternary complex with antibiotics
 
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**[[3kr6]] – EcMurA + UNAG + fosfomycin<BR />
 
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**[[3lth]] – EncMurA + UNAG + fosfomycin<BR />
 
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**[[3vcy]] – MurA + UNAG + fosfomycin – ''Vibrio fischeri''<BR />
 
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**[[4r7u]] – MurA + UNAG + fosfomycin – ''Vibrio cholerae''<BR />
 
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**[[2rl2]] – HiMurA + UNAG + fosfomycin<BR />
 
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**[[2z2c]] – EcMurA + UNAG + cnicin<BR />
 
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*MurA ternary complex
 
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**[[3su9]], [[3swa]], [[3swi]] – EncMurA (mutant) + UNAG + PEP<BR />
 
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**[[3swd]] – EcMurA (mutant) + UNAG + PEP<BR />
 
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**[[3swe]] – HiMurA (mutant) + UNAG + PEP<BR />
 
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**[[3swg]] – AaMurA + UNAG + PEP<BR />
 
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**[[6cn1]] – MurA + phosphonooxy propanoate + UNAG derivative – ''Pseudomonas putida''<BR />
 
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**[[5wi5]] – SpMurA + phosphonooxy propanoate + UNAG derivative<BR />
 
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}}
 
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 06:25, 23 June 2019

Structure of enoylpyruvate transferase complex with fosfomycin and UDP-N-acetylglucosamine (PDB entry 3kr6)

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References

  1. Brown ED, Vivas EI, Walsh CT, Kolter R. MurA (MurZ), the enzyme that catalyzes the first committed step in peptidoglycan biosynthesis, is essential in Escherichia coli. J Bacteriol. 1995 Jul;177(14):4194-7. PMID:7608103
  2. Skarzynski T, Mistry A, Wonacott A, Hutchinson SE, Kelly VA, Duncan K. Structure of UDP-N-acetylglucosamine enolpyruvyl transferase, an enzyme essential for the synthesis of bacterial peptidoglycan, complexed with substrate UDP-N-acetylglucosamine and the drug fosfomycin. Structure. 1996 Dec 15;4(12):1465-74. PMID:8994972

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Michal Harel, Alexander Berchansky

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