This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6p9e
From Proteopedia
(Difference between revisions)
m (Protected "6p9e" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of IL-36gamma complexed to A-552== | |
| - | + | <StructureSection load='6p9e' size='340' side='right'caption='[[6p9e]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6p9e]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P9E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6P9E FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=O6D:(2S)-2-{[4-(3-amino-4-methylphenyl)-6-methylpyrimidin-2-yl]oxy}-3-methoxy-3,3-diphenylpropanoic+acid'>O6D</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6p9e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p9e OCA], [http://pdbe.org/6p9e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6p9e RCSB], [http://www.ebi.ac.uk/pdbsum/6p9e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6p9e ProSAT]</span></td></tr> |
| - | [[Category: Herold, J | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/IL36G_HUMAN IL36G_HUMAN]] Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2/IL1RL2. Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Argiriadi, M A]] | ||
| + | [[Category: Gerstein, C E]] | ||
| + | [[Category: Gopalakrishnan, S M]] | ||
| + | [[Category: Henry, R F]] | ||
| + | [[Category: Herold, J M]] | ||
| + | [[Category: Honore, P]] | ||
| + | [[Category: Kakavas, S J]] | ||
| + | [[Category: McDonald, H A]] | ||
| + | [[Category: McGaraughty, S P]] | ||
[[Category: Medina, L]] | [[Category: Medina, L]] | ||
| + | [[Category: Paulsboe, S E]] | ||
| + | [[Category: Putman, B]] | ||
| + | [[Category: Qiu, W]] | ||
| + | [[Category: Richardson, P L]] | ||
| + | [[Category: Sadhukhan, R]] | ||
| + | [[Category: Salte, K M]] | ||
| + | [[Category: Scott, V E]] | ||
| + | [[Category: Shotwell, J B]] | ||
| + | [[Category: Sielaff, B]] | ||
| + | [[Category: Stockmann, H]] | ||
[[Category: Su, Z]] | [[Category: Su, Z]] | ||
| - | [[Category: | + | [[Category: Sun, C C]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
[[Category: Sun, Q]] | [[Category: Sun, Q]] | ||
| - | [[Category: Sun, C.C]] | ||
[[Category: Todorovic, T]] | [[Category: Todorovic, T]] | ||
| - | [[Category: | + | [[Category: Wetter, J B]] |
| - | [[Category: | + | [[Category: Cytokine]] |
| - | [[Category: | + | [[Category: Il-36]] |
| - | [[Category: | + | [[Category: Small molecule antagonist]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Revision as of 07:02, 26 June 2019
Crystal structure of IL-36gamma complexed to A-552
| |||||||||||
Categories: Large Structures | Argiriadi, M A | Gerstein, C E | Gopalakrishnan, S M | Henry, R F | Herold, J M | Honore, P | Kakavas, S J | McDonald, H A | McGaraughty, S P | Medina, L | Paulsboe, S E | Putman, B | Qiu, W | Richardson, P L | Sadhukhan, R | Salte, K M | Scott, V E | Shotwell, J B | Sielaff, B | Stockmann, H | Su, Z | Sun, C C | Sun, Q | Todorovic, T | Wetter, J B | Cytokine | Il-36 | Small molecule antagonist
