Fic protein

From Proteopedia

(Difference between revisions)

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 <StructureSection load="2f6s" size="350" color="" frame="true"  spin="on" Scene=  side="right" caption='Filamentation protein complex with phosphate and Zn+2 (grey), [[2f6s]]' >
+__TOC__
 == Function ==
-'''Fic protein''' ('''F'''ilamentation '''I'''nduced by '''c'''AMP) is involved in cell division.
+'''Fic protein''' ('''F'''ilamentation '''I'''nduced by '''c'''AMP) is involved in cell division<ref>PMID 26299785</ref>.
+== Structural highlights ==
 [[2f6s]] is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F6S OCA].
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 <scene name='3eqx/Active_site_spacefill/1'>Active site + spacefill</scene>
+== 3D structure of Fic protein ==
+[[Fic protein 3D structures]]
 </StructureSection>
-== 3D structure of Fic protein ==
-Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
-{{#tree:id=OrganizedByTopic|openlevels=0|
-*Fic protein
-**[[3cuc]] – Fic – ''Bacterioides thetaiotaomicron''<br />
-**[[3eqx]] – SoFic – ''Shewanella oneidensis''<br />
-**[[4rgl]] – Fic – ''Desulfovibrio alaskensis'' <br />
-**[[4u04]], [[4u07]] – hFic – human <br />
-**[[4x2e]] – PdFic – ''Peptoclostridium difficile'' <br />
-**[[4x2c]] – PdFic (mutant)  <br />
-**[[2f6s]] – Fic – ''Helicobacter pylori'' <br />
-*Fic protein complex
-**[[3s6a]] – NmFic + AMPPNP – ''Nisseria meningitidis''<br />
+== References ==
-**[[3se5]], [[3sn9]], [[3zlm]] – NmFic (mutant) + AMPPNP <br />
+<references/>
-**[[3zcn]] – SoFic Fic domain (mutant) + ATP <br />
-**[[3zec]] – SoFic Fic domain (mutant) + AMPPNP <br />
-**[[4u0s]] – hFic (mutant) + ADP <br />
-**[[4u0u]] – hFic + ADP <br />
-**[[4u0z]] – hFic + APCPP <br />
-**[[4x2d]] – PdFic (mutant) + ATP <br />
-}}
 [[Category:Topic Page]]

Current revision

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Filamentation protein complex with phosphate and Zn+2 (grey), 2f6s

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1 Function
2 Structural highlights
3 3D structure of Fic protein

Function

Fic protein (Filamentation Induced by cAMP) is involved in cell division^[1].

Structural highlights

2f6s is a 2 chains structure of sequences from Helicobacter pylori. Full crystallographic information is available from OCA.

2g03 is a 1 chain structure of sequence from Neisseria meningitidis. Full crystallographic information is available from OCA.

3cuc is a 2 chains structure of sequences from Bacteria. Full crystallographic information is available from OCA.

3eqx is a Single protein structure of sequence from Shewanella oneidensis. Full crystallographic information is available from OCA.

3D structure of Fic protein

Fic protein 3D structures

References

↑ Roy CR, Cherfils J. Structure and function of Fic proteins. Nat Rev Microbiol. 2015 Oct;13(10):631-40. doi: 10.1038/nrmicro3520. Epub 2015, Aug 24. PMID:26299785 doi:http://dx.doi.org/10.1038/nrmicro3520

Created with the participation of Tilman Schirmer.