6gtu
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==17beta-hydroxysteroid dehydrogenase 14 variant T205 in complex with fragment J6== | |
| - | + | <StructureSection load='6gtu' size='340' side='right'caption='[[6gtu]], [[Resolution|resolution]] 2.25Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6gtu]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GTU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GTU FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=45N:N-(1,3-BENZODIOXOL-5-YLMETHYL)CYCLOPENTANAMINE'>45N</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6emm|6emm]], [[6gtb|6gtb]]</td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gtu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gtu OCA], [http://pdbe.org/6gtu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gtu RCSB], [http://www.ebi.ac.uk/pdbsum/6gtu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gtu ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DHB14_HUMAN DHB14_HUMAN]] Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro).<ref>PMID:17067289</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bertoletti, N]] | ||
[[Category: Heine, A]] | [[Category: Heine, A]] | ||
| - | [[Category: Bertoletti, N]] | ||
[[Category: Klebe, G]] | [[Category: Klebe, G]] | ||
| + | [[Category: Marchais-Oberwinkler, S]] | ||
| + | [[Category: 17b-hsd14]] | ||
| + | [[Category: Fragment]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Soaking]] | ||
Revision as of 05:46, 3 July 2019
17beta-hydroxysteroid dehydrogenase 14 variant T205 in complex with fragment J6
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