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6p28
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the MIR domain (aa 337-532) of the S. cerevisiae mannosyltransferase Pmt2== | |
| - | + | <StructureSection load='6p28' size='340' side='right'caption='[[6p28]], [[Resolution|resolution]] 1.35Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6p28]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P28 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6P28 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dolichyl-phosphate-mannose--protein_mannosyltransferase Dolichyl-phosphate-mannose--protein mannosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.109 2.4.1.109] </span></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6p28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p28 OCA], [http://pdbe.org/6p28 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6p28 RCSB], [http://www.ebi.ac.uk/pdbsum/6p28 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6p28 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PMT2_YEAST PMT2_YEAST]] Protein O-mannosyltransferase involved in O-glycosylation which is essential for cell wall rigidity. Forms a heterodimeric complex with PMT2 and more rarely with PMT5 to transfer mannose from Dol-P-mannose to Ser or Thr residues on proteins. The PMT1-PMT2 complex participates in oxidative protein folding, ER-associated protein degradation (ERAD), as well as ER export.<ref>PMID:15377669</ref> <ref>PMID:18182384</ref> <ref>PMID:21147851</ref> <ref>PMID:8543034</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Dolichyl-phosphate-mannose--protein mannosyltransferase]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bai, L]] | ||
[[Category: Li, H]] | [[Category: Li, H]] | ||
| - | [[Category: | + | [[Category: Complex]] |
| + | [[Category: Glycosylation]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 05:52, 10 July 2019
Crystal structure of the MIR domain (aa 337-532) of the S. cerevisiae mannosyltransferase Pmt2
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