This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6d68
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Ube2G1 in complex with ubiquitin variant Ubv.G1.1== | |
| - | + | <StructureSection load='6d68' size='340' side='right'caption='[[6d68]], [[Resolution|resolution]] 2.36Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6d68]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D68 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D68 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/E2_ubiquitin-conjugating_enzyme E2 ubiquitin-conjugating enzyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.23 2.3.2.23] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d68 OCA], [http://pdbe.org/6d68 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d68 RCSB], [http://www.ebi.ac.uk/pdbsum/6d68 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d68 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/UB2G1_HUMAN UB2G1_HUMAN]] Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. May be involved in degradation of muscle-specific proteins. Mediates polyubiquitination of CYP3A4.<ref>PMID:19103148</ref> <ref>PMID:20061386</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: E2 ubiquitin-conjugating enzyme]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ceccarelli, D F]] | ||
| + | [[Category: Garg, P]] | ||
[[Category: Sicheri, F]] | [[Category: Sicheri, F]] | ||
[[Category: Sidhu, S]] | [[Category: Sidhu, S]] | ||
| - | [[Category: | + | [[Category: Transferase]] |
| - | [[Category: | + | [[Category: Ube2g1]] |
| + | [[Category: Ubiquitin]] | ||
| + | [[Category: Ubiquitin conjugating enzyme]] | ||
| + | [[Category: Ubiquitin variant]] | ||
Revision as of 10:36, 17 July 2019
Ube2G1 in complex with ubiquitin variant Ubv.G1.1
| |||||||||||
