NAD(P) transhydrogenase
From Proteopedia
(Difference between revisions)
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* Domain II is a membrane-spanning domain.<br /> | * Domain II is a membrane-spanning domain.<br /> | ||
* Domain III binds NADP(+)/NADPH.<br /> | * Domain III binds NADP(+)/NADPH.<br /> | ||
| - | PTH is composed of 2 subunits. | + | PTH is composed of 2 subunits. Subunit β contains domain III and part of II. The active site of PTH contains <scene name='57/571286/Cv/6'>NAD in domain I</scene> and <scene name='57/571286/Cv/7'>NADP in domain III</scene><ref>PMID:15323555</ref>. Water molecules are shown as red spheres. |
</StructureSection> | </StructureSection> | ||
Revision as of 12:18, 21 July 2019
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3D structures of NAD(P) transhydrogenase
Updated on 21-July-2019
References
- ↑ Jackson JB. Proton translocation by transhydrogenase. FEBS Lett. 2003 Jun 12;545(1):18-24. PMID:12788487
- ↑ Mather OC, Singh A, van Boxel GI, White SA, Jackson JB. Active-site conformational changes associated with hydride transfer in proton-translocating transhydrogenase. Biochemistry. 2004 Aug 31;43(34):10952-64. PMID:15323555 doi:10.1021/bi0497594
