This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Neurophysin

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:40, 23 July 2019) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
<StructureSection load='1npo' size='340' side='right' caption='Neurophysin-2 (grey and pink) complex with oxytocin (green and yellow) (PDB code [[1npo]])' scene=''>
+
<StructureSection load='' size='350' side='right' caption='Neurophysin-2 (green and cyan) complex with oxytocin (magenta and salmon) (PDB code [[1npo]])' scene='70/706270/Cv/1' pspeed='8'>
== Function ==
== Function ==
'''Neurophysins''' are carrier proteins which transport hormones from the hypothalamus to the posterior pituitary gland<ref>PMID:3147712</ref>.
'''Neurophysins''' are carrier proteins which transport hormones from the hypothalamus to the posterior pituitary gland<ref>PMID:3147712</ref>.
Line 10: Line 10:
== Disease ==
== Disease ==
Mutations in neurophysin-2 are associated with familial diabetes<ref>PMID:7714110</ref>.
Mutations in neurophysin-2 are associated with familial diabetes<ref>PMID:7714110</ref>.
 +
 +
== Structural highlights ==
 +
<scene name='70/706270/Cv/4'>Neurophysin-2/oxytocin interactions</scene>.
</StructureSection>
</StructureSection>
Line 34: Line 37:
== References ==
== References ==
<references/>
<references/>
 +
[[Category:Topic Page]]

Current revision

Neurophysin-2 (green and cyan) complex with oxytocin (magenta and salmon) (PDB code 1npo)

Drag the structure with the mouse to rotate

3D Structures of neurophysin

Updated on 23-July-2019

References

  1. ↑ Acher R, Chauvet J. Structure, processing and evolution of the neurohypophysial hormone-neurophysin precursors. Biochimie. 1988 Sep;70(9):1197-207. PMID:3147712
  2. ↑ Nagasaki H, Ito M, Yuasa H, Saito H, Fukase M, Hamada K, Ishikawa E, Katakami H, Oiso Y. Two novel mutations in the coding region for neurophysin-II associated with familial central diabetes insipidus. J Clin Endocrinol Metab. 1995 Apr;80(4):1352-6. PMID:7714110 doi:http://dx.doi.org/10.1210/jcem.80.4.7714110

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel, Joel L. Sussman

Retrieved from "http://52.214.119.220/wiki/index.php/Neurophysin"
Personal tools