6ois

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m (Protected "6ois" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 6ois is ON HOLD until Paper Publication
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==CryoEM structure of Arabidopsis DR complex (DMS3-RDM1)==
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<StructureSection load='6ois' size='340' side='right'caption='[[6ois]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6ois]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OIS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6OIS FirstGlance]. <br>
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Description:
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ois FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ois OCA], [http://pdbe.org/6ois PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ois RCSB], [http://www.ebi.ac.uk/pdbsum/6ois PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ois ProSAT]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/RDM1_ARATH RDM1_ARATH]] Regulator of RNA-directed DNA methylation (RdDM). Binds to single-stranded methyl DNA. Involved in the assembly of RNA polymerase V (Pol V) transcription initiation or elongation complexes at the chromatin, as a componant of the DDR complex.<ref>PMID:20409711</ref> <ref>PMID:20410883</ref> <ref>PMID:22864289</ref> [[http://www.uniprot.org/uniprot/DMS3_ARATH DMS3_ARATH]] Component of the RNA-directed DNA methylation (RdDM) machinery, probably by facilitating an RNAi-mediated epigenetic modification involving secondary siRNAs and spreading of DNA methylation, thus leading to gene silencing. Involved in the assembly of RNA polymerase V (Pol V) transcription initiation or elongation complexes at the chromatin, as a component of the DDR complex. Required for de novo DNA methylation.<ref>PMID:18425128</ref> <ref>PMID:19377477</ref> <ref>PMID:19915591</ref> <ref>PMID:22647529</ref> <ref>PMID:22864289</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Jacobsen, S E]]
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[[Category: Liu, S]]
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[[Category: Wongpalee, S P]]
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[[Category: Zhou, Z H]]
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[[Category: Coiled-coil]]
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[[Category: Plant protein]]
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[[Category: Rna-directed dna methylation]]
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[[Category: Smc-hinge]]
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[[Category: Snf2]]

Revision as of 06:20, 24 July 2019

CryoEM structure of Arabidopsis DR complex (DMS3-RDM1)

PDB ID 6ois

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