Nuclear transcription factor Y

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 8: Line 8:
== Structural highlights ==
== Structural highlights ==
-
<scene name='72/725371/Cv/2'>Human nuclear transcription factor Y subunit α, subunit β, subunit γ with HSP70 promoter fragment</scene> (PDB code [[4awl]]). The <scene name='72/725371/Cv/4'>interaction of NFY with the promoter CCAAT sequence, involves an insertion of an NFY helix into the minor groove of the DNA</scene><ref>PMID:23332751</ref>.
+
<scene name='72/725371/Cv/5'>Human nuclear transcription factor Y subunit α, subunit β, subunit γ with HSP70 promoter fragment</scene> (PDB code [[4awl]]). The <scene name='72/725371/Cv/6'>interaction of NFY with the promoter CCAAT sequence, involves an insertion of an NFY helix into the minor groove of the DNA</scene><ref>PMID:23332751</ref>.
</StructureSection>
</StructureSection>

Revision as of 12:41, 24 July 2019

Human nuclear transcription factor Y subunit α (cyan), subunit β (green) and subunit γ (pink) complex with HSP70 promoter DNA fragment (PDB code 4awl)

Drag the structure with the mouse to rotate

3D Structures of nuclear transcription factor Y

Updated on 24-July-2019

1n1j, 4csr – hNFY β+γ subunits - human
4awl – hNFY α+β+γ subunits + promoter DNA
5g49 – NFY β6+γ3 subunits – Arabidopsis thaliana

References

  1. ↑ Maity SN, de Crombrugghe B. Role of the CCAAT-binding protein CBF/NF-Y in transcription. Trends Biochem Sci. 1998 May;23(5):174-8. PMID:9612081
  2. ↑ Bargou RC, Jurchott K, Wagener C, Bergmann S, Metzner S, Bommert K, Mapara MY, Winzer KJ, Dietel M, Dorken B, Royer HD. Nuclear localization and increased levels of transcription factor YB-1 in primary human breast cancers are associated with intrinsic MDR1 gene expression. Nat Med. 1997 Apr;3(4):447-50. PMID:9095180
  3. ↑ Nardini M, Gnesutta N, Donati G, Gatta R, Forni C, Fossati A, Vonrhein C, Moras D, Romier C, Bolognesi M, Mantovani R. Sequence-Specific Transcription Factor NF-Y Displays Histone-like DNA Binding and H2B-like Ubiquitination. Cell. 2013 Jan 17;152(1-2):132-43. doi: 10.1016/j.cell.2012.11.047. PMID:23332751 doi:http://dx.doi.org/10.1016/j.cell.2012.11.047

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

Retrieved from "http://52.214.119.220/wiki/index.php/Nuclear_transcription_factor_Y"
Personal tools