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6foz
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The crystal structure of P.fluorescens Kynurenine 3-monooxygenase (KMO) in complex with competitive inhibitor No. 13== |
| - | + | <StructureSection load='6foz' size='340' side='right'caption='[[6foz]], [[Resolution|resolution]] 2.15Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6foz]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FOZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FOZ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=E0H:5-(3,4-dichlorophenyl)furan-2-carboxylic+acid'>E0H</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Kynurenine_3-monooxygenase Kynurenine 3-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.9 1.14.13.9] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6foz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6foz OCA], [http://pdbe.org/6foz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6foz RCSB], [http://www.ebi.ac.uk/pdbsum/6foz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6foz ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/KMO_PSEFL KMO_PSEFL]] Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Probably required for the synthesis of quinolinic acid and the siderophore quinolobactin. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Kynurenine 3-monooxygenase]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Levy, C W]] | ||
| + | [[Category: Leys, D]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 05:51, 21 August 2019
The crystal structure of P.fluorescens Kynurenine 3-monooxygenase (KMO) in complex with competitive inhibitor No. 13
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