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6q6c
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Pore-modulating toxins exploit inherent slow inactivation to block K+ channels== | |
| - | + | <StructureSection load='6q6c' size='340' side='right'caption='[[6q6c]], [[Resolution|resolution]] 1.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6q6c]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Q6C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6Q6C FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6q6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6q6c OCA], [http://pdbe.org/6q6c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6q6c RCSB], [http://www.ebi.ac.uk/pdbsum/6q6c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6q6c ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/VKTS1_CONST VKTS1_CONST]] Blocks specifically voltage-activated potassium channels (Kv) of the Shaker family (IC(50)=1.33 nM).<ref>PMID:15833744</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Dym, O]] | ||
| + | [[Category: Fine, S]] | ||
| + | [[Category: Frolow, F]] | ||
| + | [[Category: Gordon, D]] | ||
| + | [[Category: Gueta, H]] | ||
| + | [[Category: Gurevitz, M]] | ||
| + | [[Category: Hamer-Rogotner, S]] | ||
[[Category: Karbat, I]] | [[Category: Karbat, I]] | ||
[[Category: Panyi, G]] | [[Category: Panyi, G]] | ||
| - | [[Category: | + | [[Category: Reuveny, E]] |
[[Category: Szanto, T]] | [[Category: Szanto, T]] | ||
| - | [[Category: | + | [[Category: Toxin]] |
| - | + | ||
| - | + | ||
| - | + | ||
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Revision as of 06:06, 21 August 2019
Pore-modulating toxins exploit inherent slow inactivation to block K+ channels
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Categories: Large Structures | Dym, O | Fine, S | Frolow, F | Gordon, D | Gueta, H | Gurevitz, M | Hamer-Rogotner, S | Karbat, I | Panyi, G | Reuveny, E | Szanto, T | Toxin
