Ribosomal protein L11 methyltransferase
From Proteopedia
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| - | <StructureSection load=' | + | <StructureSection load='' size='350' side='right' caption='Structure of ribosomal protein L11 methyltransferase (deepskyblue) complex with 50S ribosomal protein L11 (green) (PDB entry [[2nxn]])' scene='42/423383/Cv/2'> |
== Function == | == Function == | ||
[[Ribosomal protein L11 methyltransferase]] (L11 MTase) catalyzes the methylation of ribosomal protein L11 (RPL11)<ref>PMID:10997488</ref>. | [[Ribosomal protein L11 methyltransferase]] (L11 MTase) catalyzes the methylation of ribosomal protein L11 (RPL11)<ref>PMID:10997488</ref>. | ||
== Structural highlights == | == Structural highlights == | ||
| - | L11 MTase methylates the N terminal of RPL11 and residues Lys3 and Lys39.<ref>PMID:17215866</ref> | + | L11 MTase methylates the <scene name='42/423383/Cv/4'>N terminal of RPL11 and residues Lys3 and Lys39</scene>.<ref>PMID:17215866</ref> |
</StructureSection> | </StructureSection> | ||
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**[[2nxc]], [[2nxj]] - TtL11 MTase - ''Thermus thermophilus''<br /> | **[[2nxc]], [[2nxj]] - TtL11 MTase - ''Thermus thermophilus''<br /> | ||
**[[2zbp]], [[2zbq]], [[2zbr]], [[2nxe]]– TtL11 MTase+S-adenosyl derivatives <br /> | **[[2zbp]], [[2zbq]], [[2zbr]], [[2nxe]]– TtL11 MTase+S-adenosyl derivatives <br /> | ||
| + | **[[5fa8]] - SiL11 MTase + SAM - ''Sulfolobus islandicus''<br /> | ||
| + | **[[5fad]] - SiL11 MTase + SAH <br /> | ||
*Ribosomal protein L11 methyltransferase+Ribosomal protein L11 | *Ribosomal protein L11 methyltransferase+Ribosomal protein L11 | ||
Current revision
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3D Structures of Ribosomal protein L11 methyltransferase
References
- ↑ Bujnicki JM. Sequence, structural, and evolutionary analysis of prokaryotic ribosomal protein L11 methyltransferases. Acta Microbiol Pol. 2000;49(1):19-29. PMID:10997488
- ↑ Demirci H, Gregory ST, Dahlberg AE, Jogl G. Recognition of ribosomal protein L11 by the protein trimethyltransferase PrmA. EMBO J. 2007 Jan 24;26(2):567-77. Epub 2007 Jan 11. PMID:17215866
