Integrin
From Proteopedia
(Difference between revisions)
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<scene name='51/516472/Cv/4'>Mg/Cl coordination site</scene>. Water molecules shown as red spheres. | <scene name='51/516472/Cv/4'>Mg/Cl coordination site</scene>. Water molecules shown as red spheres. | ||
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| + | ==3D structures of integrin== | ||
| + | [[Integrin 3D structures]] | ||
</StructureSection> | </StructureSection> | ||
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**[[1dzi]], [[4bj3]] - hIG I domain + collagen peptide<br /> | **[[1dzi]], [[4bj3]] - hIG I domain + collagen peptide<br /> | ||
**[[1v7p]] - hIG I domain (mutant) + EMS16 + Mn<br /> | **[[1v7p]] - hIG I domain (mutant) + EMS16 + Mn<br /> | ||
| - | **[[5thp]] - hIG residues 170-366 + rhodocetin <br /> | + | **[[5thp]], [[6nd8]], [[6nd9]], [[6nda]], [[6ndb]], [[6ndc]], [[6ndd]], [[6nde]], [[6ndf]], [[6ndg]], [[6ndh]] - hIG residues 170-366 + rhodocetin <br /> |
*IG α-2b | *IG α-2b | ||
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**[[2lke]], [[2lkj]] – hIG cytoplasmic domain – NMR<BR /> | **[[2lke]], [[2lkj]] – hIG cytoplasmic domain – NMR<BR /> | ||
**[[4xw2]] – hIG + simvastatin<br /> | **[[4xw2]] – hIG + simvastatin<br /> | ||
| + | |||
| + | *IG α-V β-8 | ||
| + | |||
| + | **[[6djp]] – hIG + antibody – Cryo EM<br /> | ||
*IG α-X | *IG α-X | ||
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**[[2p26]], [[2p28]], [[5e6w]] – hIG phe2 + phe3 domains<br /> | **[[2p26]], [[2p28]], [[5e6w]] – hIG phe2 + phe3 domains<br /> | ||
**[[1yuk]] – hIG chain A PSI domain + chain B I-EGF domain<br /> | **[[1yuk]] – hIG chain A PSI domain + chain B I-EGF domain<br /> | ||
| + | **[[5zaz]] – hIG transmembrane domain - NMR<br /> | ||
*IG β-3 (CD61) | *IG β-3 (CD61) | ||
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**[[2mtp]] – hIG cytoplasmic tail (mutant) + hIG α-2 β peptide+ filamin rod domain<br /> | **[[2mtp]] – hIG cytoplasmic tail (mutant) + hIG α-2 β peptide+ filamin rod domain<br /> | ||
| - | *IG β-4 (CD104) | + | *IG β-4 (CD104; Gp150) |
**[[2f7q]], [[3f7r]], [[1qg3]], [[3f7q]], [[4wtw]], [[4wtx]] - hIG fibronectin type III domain<br /> | **[[2f7q]], [[3f7r]], [[1qg3]], [[3f7q]], [[4wtw]], [[4wtx]] - hIG fibronectin type III domain<br /> | ||
**[[2yrz]] – hIG fibronectin type III domain – NMR<BR /> | **[[2yrz]] – hIG fibronectin type III domain – NMR<BR /> | ||
**[[3f7p]], [[4q58]] - hIG fibronectin type III domain + plectin-1 <br /> | **[[3f7p]], [[4q58]] - hIG fibronectin type III domain + plectin-1 <br /> | ||
| - | **[[3fq4]], [[3fso]], [[3h6a]] – hIG Calx-β domain | + | **[[6gvl]] - hIG fibronectin type III domain + dystonin<br /> |
| + | **[[6gvk]] - hIG fibronectin type III domain (mutant) + dystonin<br /> | ||
| + | **[[3fq4]], [[3fso]], [[3h6a]] – hIG Calx-β domain<br /> | ||
| + | **[[6hyf]] - rIG fibronectin type III domain <br /> | ||
*IG β-7 | *IG β-7 | ||
Revision as of 10:23, 29 August 2019
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3D structures of integrin
Updated on 29-August-2019
References
- ↑ Humphries MJ. Integrin structure. Biochem Soc Trans. 2000;28(4):311-39. PMID:10961914
- ↑ Hillis GS, MacLeod AM. Integrins and disease. Clin Sci (Lond). 1996 Dec;91(6):639-50. PMID:8976799
- ↑ Larjava H, Koivisto L, Heino J, Hakkinen L. Integrins in periodontal disease. Exp Cell Res. 2014 Jul 15;325(2):104-10. doi: 10.1016/j.yexcr.2014.03.010. Epub, 2014 Mar 22. PMID:24662197 doi:http://dx.doi.org/10.1016/j.yexcr.2014.03.010
- ↑ Humphries MJ. Integrin structure. Biochem Soc Trans. 2000;28(4):311-39. PMID:10961914
