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6f0a
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==Crystal structure of human indoleamine 2,3-dioxygenase bound to a triazole inhibitor and alanine molecule.== | ==Crystal structure of human indoleamine 2,3-dioxygenase bound to a triazole inhibitor and alanine molecule.== | ||
| - | <StructureSection load='6f0a' size='340' side='right' caption='[[6f0a]], [[Resolution|resolution]] 2.26Å' scene=''> | + | <StructureSection load='6f0a' size='340' side='right'caption='[[6f0a]], [[Resolution|resolution]] 2.26Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6f0a]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F0A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6F0A FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6f0a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F0A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6F0A FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=C82:~{N}-(4-chlorophenyl)-1~{H}-1,2,3-triazol-5-amine'>C82</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=C82:~{N}-(4-chlorophenyl)-1~{H}-1,2,3-triazol-5-amine'>C82</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IDO1, IDO, INDO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Indoleamine_2,3-dioxygenase Indoleamine 2,3-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.52 1.13.11.52] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Indoleamine_2,3-dioxygenase Indoleamine 2,3-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.52 1.13.11.52] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6f0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f0a OCA], [http://pdbe.org/6f0a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6f0a RCSB], [http://www.ebi.ac.uk/pdbsum/6f0a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6f0a ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6f0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f0a OCA], [http://pdbe.org/6f0a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6f0a RCSB], [http://www.ebi.ac.uk/pdbsum/6f0a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6f0a ProSAT]</span></td></tr> | ||
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</div> | </div> | ||
<div class="pdbe-citations 6f0a" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 6f0a" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Dioxygenase 3D structures|Dioxygenase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Indoleamine 2,3-dioxygenase]] | [[Category: Indoleamine 2,3-dioxygenase]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Latchem, M]] | [[Category: Latchem, M]] | ||
[[Category: Swan, M K]] | [[Category: Swan, M K]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Tryptophan 2 3 dioxygenase activity electron transfer activity oxidoreductase activity heme binding indoleamine 2 3 dioxygenase activity metal ion binding dioxygenase activity]] | [[Category: Tryptophan 2 3 dioxygenase activity electron transfer activity oxidoreductase activity heme binding indoleamine 2 3 dioxygenase activity metal ion binding dioxygenase activity]] | ||
Current revision
Crystal structure of human indoleamine 2,3-dioxygenase bound to a triazole inhibitor and alanine molecule.
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