Vanillyl-alcohol oxidase

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{{STRUCTURE_3fim| PDB=3fim | SIZE=400| SCENE= |right|CAPTION=Vanillyl-alcohol oxidase containing FAD, [[3fim]] }}
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<StructureSection load='' size='350' side='right' caption='Vanillyl-alcohol oxidase containing FAD, [[3fim]]' scene='48/486449/Cv/1' >
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== Function ==
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'''Vanillyl-alcohol oxidase''' (VAO) catalyzes the conversion of vanillyl alcohol and molecular oxygen to vaniline and hydrogen peroxide. VAO is part of the 2,4-dichlorobenzoate degradation and uses FAD as a cofactor<ref>PMID:16232469</ref>.
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Please use the "3D" button above this box to insert a Jmol applet (molecule) on this page.
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*<scene name='48/486449/Cv/4'>FAD binding site</scene> in Vanillyl-alcohol oxidase ([[3fim]]).
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== Relevance ==
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to a Jmol applet. Check out the other buttons as well!
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VAO is a versatile biocatalyst and converts a wide variety of phenolic compounds<ref>PMID:10653736</ref>.
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</StructureSection>
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'''Vanillyl-alcohol oxidase''' (VAO) catalyzes the conversion of vanillyl alcohol and molecular oxygen to vaniline and hydrogen peroxide. VAO is a versatile biocatalyst and converts a wide variety of phenolic compounds. VAO is part of the 2,4-dichlorobenzoate degradation and uses FAD as a cofactor.
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==3D structures of vanillyl-alcohol oxidase==
==3D structures of vanillyl-alcohol oxidase==
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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[[1ahu]], [[1vao]] – PsVAO – ''Penicillium simplicissimum''<br />
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*Vanillyl-alcohol oxidase
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[[1qlt]], [[1dzn]], [[1e0y]] – PsVAO (mutant)<br />
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[[3fim]] – VAO – ''Pleurotus eryngii''
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'''Apo vanillyl-alcohol oxidase'''
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**[[1vao]] – PsVAO + FAD – ''Penicillium simplicissimum''<br />
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**[[1ahu]] – PsVAO + FAD derivative<br />
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**[[1qlt]], [[1dzn]], [[1e0y]], [[5mxj]], [[5mxu]] – PsVAO (mutant) + FAD<br />
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**[[3fim]] – VAO + FAD – ''Pleurotus eryngii''
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[[1e8f]] - PsVAO (mutant) <br />
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*Apo vanillyl-alcohol oxidase
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[[1e8h]] - PsVAO (mutant) + ADP
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'''Vanillyl-alcohol oxidase binary complex'''
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**[[1e8f]] - PsVAO (mutant) <br />
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**[[1e8h]] - PsVAO (mutant) + ADP
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[[1ahv]] – PsVAO + nitro-cresol<br />
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*Vanillyl-alcohol oxidase binary complex
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[[1ahz]], [[2vao]] – PsVAO + phenol derivative<br />
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[[1qlu]], [[1w1j]], [[1w1k]], [[1w1l]], [[1w1m]] - PsVAO (mutant) + phenol derivative<br />
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[[1e8g]] - PsVAO (mutant) + cresol derivative
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**[[1ahv]] – PsVAO + FAD + nitro-cresol<br />
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**[[1ahz]], [[2vao]] – PsVAO + FAD + phenol derivative<br />
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**[[1qlu]], [[1w1j]], [[1w1k]], [[1w1l]], [[1w1m]] - PsVAO (mutant) + FAD + phenol derivative<br />
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**[[1e8g]] - PsVAO (mutant) + FAD + cresol derivative
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}}
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==References==
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<references />
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Vanillyl-alcohol oxidase containing FAD, 3fim

Drag the structure with the mouse to rotate

3D structures of vanillyl-alcohol oxidase

Updated on 16-October-2019

References

  1. ↑ Furukawa H, Wieser M, Morita H, Sugio T, Nagasawa T. Purification and characterization of vanillyl-alcohol oxidase from Byssochlamys fulva V107. J Biosci Bioeng. 1999;87(3):285-90. PMID:16232469
  2. ↑ Li T, Rosazza JP. Biocatalytic synthesis of vanillin. Appl Environ Microbiol. 2000 Feb;66(2):684-7. PMID:10653736

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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