6-phosphogluconate dehydrogenase

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'''6-phosphogluconate dehydrogenase''' (6PGD) catalyzes the decarboxylation reduction of 6-phosphogluconate (6PG) to ribulose 5-phosphate and CO2. This reaction is part of the pentose phosphate pathway. NADP is a cofactor in this reaction and is converted to NADPH.<ref>PMID:7922402</ref>
'''6-phosphogluconate dehydrogenase''' (6PGD) catalyzes the decarboxylation reduction of 6-phosphogluconate (6PG) to ribulose 5-phosphate and CO2. This reaction is part of the pentose phosphate pathway. NADP is a cofactor in this reaction and is converted to NADPH.<ref>PMID:7922402</ref>
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*<scene name='49/491981/Cv/4'>NADP interactions</scene> with Sheep 6-phosphogluconate dehydrogenase (PDB code [[1pgo]]).
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*<scene name='49/491981/Cv/4'>NADP interactions</scene> with Sheep 6-phosphogluconate dehydrogenase (PDB code [[1pgo]]). Water molecules are shown as red spheres.
*<scene name='49/491981/Cv/5'>NADP binding cavity</scene>.
*<scene name='49/491981/Cv/5'>NADP binding cavity</scene>.

Revision as of 13:53, 28 October 2019

Sheep 6-phosphogluconate dehydrogenase complex with cofactor NADP and sulfate (PDB code 1pgo)

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References

  1. Beam TR Jr. Quinolone therapy in intensive care unit settings. New Horiz. 1993 May;1(2):187-93. PMID:7922402
  2. Monga A, Makkar RP, Arora A, Mukhopadhyay S, Gupta AK. Case report: Acute hepatitis E infection with coexistent glucose-6-phosphate dehydrogenase deficiency. Can J Infect Dis. 2003 Jul;14(4):230-1. PMID:18159462

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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