This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6qb6
From Proteopedia
(Difference between revisions)
m (Protected "6qb6" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Mcl1 in complex with a Fab== | |
| - | + | <StructureSection load='6qb6' size='340' side='right'caption='[[6qb6]], [[Resolution|resolution]] 2.24Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6qb6]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QB6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QB6 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6qb3|6qb3]], [[6qb4|6qb4]], [[6fs0|6fs0]]</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qb6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qb6 OCA], [http://pdbe.org/6qb6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qb6 RCSB], [http://www.ebi.ac.uk/pdbsum/6qb6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qb6 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MCL1_HUMAN MCL1_HUMAN]] Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.<ref>PMID:10766760</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Hargreaves, D]] | [[Category: Hargreaves, D]] | ||
| + | [[Category: Apoptosis]] | ||
| + | [[Category: Azd5991]] | ||
| + | [[Category: Fab]] | ||
| + | [[Category: Mcl1]] | ||
Revision as of 06:47, 6 November 2019
Mcl1 in complex with a Fab
| |||||||||||
Categories: Large Structures | Hargreaves, D | Apoptosis | Azd5991 | Fab | Mcl1
