Ornithine carbamoyltransferase
From Proteopedia
(Difference between revisions)
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</StructureSection> | </StructureSection> | ||
| - | ==3D structures of ornithine carbamoyltransferase== | ||
| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | *Ornithine carbamoyltransferase | ||
| - | |||
| - | **[[1a1s]], [[1pvv]] – OTC – ''Pyrococcus furiosus''<br /> | ||
| - | **[[2ef0]] – OTC – ''Thermus thermophilus''<br /> | ||
| - | **[[2p2g]] – MtOTC – ''Mycobacterium tuberculosis''<br /> | ||
| - | **[[3gd5]] – OTC – ''Gleobacter violaceus''<br /> | ||
| - | **[[3grf]] – OTC – ''Giardia intestinalis''<br /> | ||
| - | **[[3upd]], [[4kwt]] – VvOTC – ''Vibrio vulnificus''<br /> | ||
| - | **[[3sds]] – OTC – valley fever fungus<br /> | ||
| - | **[[6ovw]] – OTC – ''Salmonella typhimurium''<br /> | ||
| - | |||
| - | *Catabolic ornithine carbamoyltransferase | ||
| - | |||
| - | **[[1dxh]] – PaOTC – ''Pseudomonas aeruginosa''<br /> | ||
| - | **[[1ort]] – PaOTC (mutant) <br /> | ||
| - | **[[2w37]] – OTC – ''Lactobacillus hilgardii''<br /> | ||
| - | **[[4amu]], [[4anf]] – OTC – ''Mycoplasma penetrans''<br /> | ||
| - | **[[4oh7]] – OTC – ''Brucella melitensis''<br /> | ||
| - | |||
| - | *Anabolic ornithine carbamoyltransferase | ||
| - | |||
| - | **[[4kwt]] – VvOTC <br /> | ||
| - | **[[4ep1]] – BaOTC (mutant) – ''Bacillus anthracis''<br /> | ||
| - | **[[3tpf]] – OTC – ''Campylobacter jejuni''<br /> | ||
| - | **[[1akm]] – EcOTC – ''Escherichia coli''<br /> | ||
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| - | *Ornithine carbamoyltransferase complex | ||
| - | |||
| - | **[[1vlv]] – OTC + phosphate – ''Thermotoga maritima''<br /> | ||
| - | **[[2i6u]] – MtOTC + norvaline + carbamoyl phosphate <br /> | ||
| - | **[[4f2g]] – OTC + phosphate – ''Burkholderia thailandensis''<br /> | ||
| - | **[[1c9y]] – hOTC + norvaline + carbamoyl phosphate - human<br /> | ||
| - | **[[1ep9]], [[1fvo]] – hOTC + CP <br /> | ||
| - | **[[1oth]] – hOTC + ornithine derivative<br /> | ||
| - | **[[1duv]], [[2otc]] – EcOTC + ornithine derivative<br /> | ||
| - | **[[1fb5]] – sOTC + norvaline - sheep<br /> | ||
| - | |||
| - | *Anabolic ornithine carbamoyltransferase complex | ||
| - | |||
| - | **[[4h31]] – VvOTC + norvaline + carbamoyl phosphate<br /> | ||
| - | **[[4jfr]] – VvOTC + carbamoyl phosphate<br /> | ||
| - | **[[4jhx]] – VvOTC + arginine + carbamoyl phosphate<br /> | ||
| - | **[[4jqo]] – VvOTC + citrulline + phosphate<br /> | ||
| - | **[[4nf2]] – BaOTC (mutant) + norvaline + carbamoyl phosphate<br /> | ||
| - | |||
| - | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
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References
- ↑ Murata LB, Schachman HK. Structural similarity between ornithine and aspartate transcarbamoylases of Escherichia coli: characterization of the active site and evidence for an interdomain carboxy-terminal helix in ornithine transcarbamoylase. Protein Sci. 1996 Apr;5(4):709-18. PMID:8845761 doi:http://dx.doi.org/10.1002/pro.5560050416
- ↑ Storkanova G, Vlaskova H, Chuzhanova N, Zeman J, Stranecky V, Majer F, Peskova K, Luksan O, Jirsa M, Hrebicek M, Dvorakova L. Ornithine carbamoyltransferase deficiency: molecular characterization of 29 families. Clin Genet. 2013 Dec;84(6):552-9. doi: 10.1111/cge.12085. Epub 2013 Feb 7. PMID:23278509 doi:http://dx.doi.org/10.1111/cge.12085
- ↑ Sankaranarayanan R, Cherney MM, Cherney LT, Garen CR, Moradian F, James MN. The crystal structures of ornithine carbamoyltransferase from Mycobacterium tuberculosis and its ternary complex with carbamoyl phosphate and L-norvaline reveal the enzyme's catalytic mechanism. J Mol Biol. 2008 Jan 25;375(4):1052-63. Epub 2007 Nov 19. PMID:18062991 doi:10.1016/j.jmb.2007.11.025
