Phosphoribosylaminoimidazole carboxylase

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== Structural highlights ==
== Structural highlights ==
The biological assembly of ''E. coli'' PurE is <scene name='57/571253/Cv/5'>octamer</scene>. PurE <scene name='57/571253/Cv/6'>active site</scene> is located in a <scene name='57/571253/Cv/7'>cleft between 3 subunits</scene><ref>PMID:10574791</ref>. Water molecule is shown as red sphere.
The biological assembly of ''E. coli'' PurE is <scene name='57/571253/Cv/5'>octamer</scene>. PurE <scene name='57/571253/Cv/6'>active site</scene> is located in a <scene name='57/571253/Cv/7'>cleft between 3 subunits</scene><ref>PMID:10574791</ref>. Water molecule is shown as red sphere.
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==3D structures of PurE==
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[[Phosphoribosylaminoimidazole carboxylase 3D structures]]
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</StructureSection>
</StructureSection>
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**[[2nsj]], [[2nsl]] - EcPurE (mutant) + CAIR<br />
**[[2nsj]], [[2nsl]] - EcPurE (mutant) + CAIR<br />
**[[3opq]] – FtPurE + fructose-6-phosphate<br />
**[[3opq]] – FtPurE + fructose-6-phosphate<br />
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**[[3k5h]] – AcPurE + ATP – ''Aspergillus clavatus''<br />
 +
**[[3k5i]] – AcPurE + ADP + AIR<br />
*PurK
*PurK

Revision as of 10:46, 18 November 2019

Structure of E. coli PurE octamer complex with 5-aminoimidazole ribonucleotide (AIR) (PDB entry 1d7a)

Drag the structure with the mouse to rotate

3D structures of PurE

Updated on 18-November-2019

References

  1. Meyer E, Leonard NJ, Bhat B, Stubbe J, Smith JM. Purification and characterization of the purE, purK, and purC gene products: identification of a previously unrecognized energy requirement in the purine biosynthetic pathway. Biochemistry. 1992 Jun 2;31(21):5022-32. PMID:1534690
  2. Mathews II, Kappock TJ, Stubbe J, Ealick SE. Crystal structure of Escherichia coli PurE, an unusual mutase in the purine biosynthetic pathway. Structure. 1999 Nov 15;7(11):1395-406. PMID:10574791

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman, Jaime Prilusky

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