Ubiquitin
From Proteopedia
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==Additional Resources== | ==Additional Resources== | ||
| - | See: [[Tumor susceptibility gene 101]] | + | See also: |
| - | + | *[[Tumor susceptibility gene 101]] | |
| + | *SUMO | ||
== Disease == | == Disease == | ||
The UBB-proteasome system deregulation has been implicated in the pathogenesis of many neurodegenerative disorders like Alzheimer's disease, Parkinson disease, Huntington disease, Prion-like lethal disorders and in genetic diseases like cystic fibrosis, angelman's syndrome, Liddle syndrome and many cancers<ref>PMID:18937370</ref>. | The UBB-proteasome system deregulation has been implicated in the pathogenesis of many neurodegenerative disorders like Alzheimer's disease, Parkinson disease, Huntington disease, Prion-like lethal disorders and in genetic diseases like cystic fibrosis, angelman's syndrome, Liddle syndrome and many cancers<ref>PMID:18937370</ref>. | ||
Revision as of 14:52, 18 November 2019
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3D Structures of Ubiquitin
Updated on 18-November-2019
References
- ↑ Hershko A, Ciechanover A. The ubiquitin system. Annu Rev Biochem. 1998;67:425-79. PMID:9759494 doi:http://dx.doi.org/10.1146/annurev.biochem.67.1.425
- ↑ Paul S. Dysfunction of the ubiquitin-proteasome system in multiple disease conditions: therapeutic approaches. Bioessays. 2008 Nov;30(11-12):1172-84. doi: 10.1002/bies.20852. PMID:18937370 doi:http://dx.doi.org/10.1002/bies.20852
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Michal Harel, Alexander Berchansky, Joel L. Sussman, David Canner, Jaime Prilusky

