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6nl3

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m (Protected "6nl3" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 6nl3 is ON HOLD until Paper Publication
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==Solution structure of human Coa6==
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<StructureSection load='6nl3' size='340' side='right'caption='[[6nl3]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6nl3]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NL3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NL3 FirstGlance]. <br>
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Description:
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nl3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nl3 OCA], [http://pdbe.org/6nl3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nl3 RCSB], [http://www.ebi.ac.uk/pdbsum/6nl3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nl3 ProSAT]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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== Disease ==
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[[http://www.uniprot.org/uniprot/COA6_HUMAN COA6_HUMAN]] Fatal infantile cytochrome C oxidase deficiency. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[[http://www.uniprot.org/uniprot/COA6_HUMAN COA6_HUMAN]] Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2. Thereby, may regulate early steps of complex IV assembly. Mitochondrial respiratory chain complex IV or cytochrome c oxidase is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence contributes to the proton gradient involved in mitochondrial ATP synthesis. May also be required for efficient formation of respiratory supercomplexes comprised of complexes III and IV.<ref>PMID:24549041</ref> <ref>PMID:25959673</ref> <ref>PMID:26160915</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Gohil, V]]
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[[Category: Naik, M T]]
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[[Category: Soma, S]]
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[[Category: Mitochondrial protein]]
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[[Category: Oxidoreductase]]

Revision as of 15:27, 20 November 2019

Solution structure of human Coa6

PDB ID 6nl3

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OCA

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