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6q03
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of MurA from Clostridium difficile in the presence of UDP-N-acetyl-alpha-D-muramic acid with modified Cys116 (S-[(1S)-1-carboxy-1-(phosphonooxy)ethyl]-L-cysteine)== | |
| - | + | <StructureSection load='6q03' size='340' side='right'caption='[[6q03]], [[Resolution|resolution]] 1.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6q03]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Q03 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6Q03 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPZ:(2R)-2-{[(2R,3R,4R,5S,6R)-3-(ACETYLAMINO)-2-{[(S)-{[(R)-{[(2R,3S,4R,5R)-5-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-5-HYDROXY-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-4-YL]OXY}PROPANOIC+ACID'>EPZ</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=QPA:S-[(1S)-1-CARBOXY-1-(PHOSPHONOOXY)ETHYL]-L-CYSTEINE'>QPA</scene></td></tr> |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_1-carboxyvinyltransferase UDP-N-acetylglucosamine 1-carboxyvinyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.7 2.5.1.7] </span></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6q03 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6q03 OCA], [http://pdbe.org/6q03 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6q03 RCSB], [http://www.ebi.ac.uk/pdbsum/6q03 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6q03 ProSAT]</span></td></tr> |
| - | [[Category: Dopkins, B | + | </table> |
| - | [[Category: Holden, H | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/Q18CL1_CLOD6 Q18CL1_CLOD6]] Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.[HAMAP-Rule:MF_00111][SAAS:SAAS00767217] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: UDP-N-acetylglucosamine 1-carboxyvinyltransferase]] | ||
| + | [[Category: Call, C J]] | ||
| + | [[Category: Dopkins, B J]] | ||
| + | [[Category: Holden, H M]] | ||
| + | [[Category: Thoden, J B]] | ||
| + | [[Category: Antibiotic]] | ||
| + | [[Category: Clostridium difficile]] | ||
| + | [[Category: Peptidoglycan]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 06:54, 27 November 2019
Crystal structure of MurA from Clostridium difficile in the presence of UDP-N-acetyl-alpha-D-muramic acid with modified Cys116 (S-[(1S)-1-carboxy-1-(phosphonooxy)ethyl]-L-cysteine)
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