This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4x3v
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal structure of human ribonucleotide reductase 1 bound to inhibitor== | ==Crystal structure of human ribonucleotide reductase 1 bound to inhibitor== | ||
| - | <StructureSection load='4x3v' size='340' side='right' caption='[[4x3v]], [[Resolution|resolution]] 3.70Å' scene=''> | + | <StructureSection load='4x3v' size='340' side='right'caption='[[4x3v]], [[Resolution|resolution]] 3.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4x3v]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X3V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X3V FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4x3v]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X3V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X3V FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3X4:N~6~-{N-[(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)ACETYL]-2-METHYL-D-ALANYL}-D-LYSINE'>3X4</scene>, <scene name='pdbligand=TTP:THYMIDINE-5-TRIPHOSPHATE'>TTP</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3X4:N~6~-{N-[(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)ACETYL]-2-METHYL-D-ALANYL}-D-LYSINE'>3X4</scene>, <scene name='pdbligand=TTP:THYMIDINE-5-TRIPHOSPHATE'>TTP</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RRM1, RR1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x3v OCA], [http://pdbe.org/4x3v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x3v RCSB], [http://www.ebi.ac.uk/pdbsum/4x3v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4x3v ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x3v OCA], [http://pdbe.org/4x3v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x3v RCSB], [http://www.ebi.ac.uk/pdbsum/4x3v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4x3v ProSAT]</span></td></tr> | ||
| Line 19: | Line 20: | ||
</div> | </div> | ||
<div class="pdbe-citations 4x3v" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4x3v" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Ribonucleotide reductase|Ribonucleotide reductase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Ribonucleoside-diphosphate reductase]] | [[Category: Ribonucleoside-diphosphate reductase]] | ||
[[Category: Ahmad, M F]] | [[Category: Ahmad, M F]] | ||
Revision as of 08:42, 4 December 2019
Crystal structure of human ribonucleotide reductase 1 bound to inhibitor
| |||||||||||
