This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5t0m
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==A histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreading== | ==A histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreading== | ||
| - | <StructureSection load='5t0m' size='340' side='right' caption='[[5t0m]], [[Resolution|resolution]] 1.90Å' scene=''> | + | <StructureSection load='5t0m' size='340' side='right'caption='[[5t0m]], [[Resolution|resolution]] 1.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5t0m]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T0M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T0M FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5t0m]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T0M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T0M FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NLE:NORLEUCINE'>NLE</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NLE:NORLEUCINE'>NLE</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5t0k|5t0k]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5t0k|5t0k]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EHMT2, BAT8, C6orf30, G9A, KMT1C, NG36 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t0m OCA], [http://pdbe.org/5t0m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t0m RCSB], [http://www.ebi.ac.uk/pdbsum/5t0m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t0m ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t0m OCA], [http://pdbe.org/5t0m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t0m RCSB], [http://www.ebi.ac.uk/pdbsum/5t0m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t0m ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| Line 20: | Line 21: | ||
</div> | </div> | ||
<div class="pdbe-citations 5t0m" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5t0m" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Histone methyltransferase 3D structures|Histone methyltransferase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Tong, L]] | [[Category: Tong, L]] | ||
[[Category: Xu, K]] | [[Category: Xu, K]] | ||
Revision as of 09:21, 4 December 2019
A histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreading
| |||||||||||
