This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5wfm
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal structure of the influenza virus PA endonuclease (E119D mutant) in complex with inhibitor 10e (SRI-30024)== | ==Crystal structure of the influenza virus PA endonuclease (E119D mutant) in complex with inhibitor 10e (SRI-30024)== | ||
| - | <StructureSection load='5wfm' size='340' side='right' caption='[[5wfm]], [[Resolution|resolution]] 2.25Å' scene=''> | + | <StructureSection load='5wfm' size='340' side='right'caption='[[5wfm]], [[Resolution|resolution]] 2.25Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5wfm]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WFM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WFM FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5wfm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/I09a0 I09a0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WFM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WFM FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KU5:2-[(2S)-1-{[(2-chlorophenyl)sulfanyl]acetyl}pyrrolidin-2-yl]-5-hydroxy-6-oxo-N-[2-(phenylsulfonyl)ethyl]-1,6-dihydropyrimidine-4-carboxamide'>KU5</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KU5:2-[(2S)-1-{[(2-chlorophenyl)sulfanyl]acetyl}pyrrolidin-2-yl]-5-hydroxy-6-oxo-N-[2-(phenylsulfonyl)ethyl]-1,6-dihydropyrimidine-4-carboxamide'>KU5</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5w3i|5w3i]], [[5w44|5w44]], [[5wef|5wef]], [[5wei|5wei]], [[5we9|5we9]], [[5w73|5w73]], [[5w7u|5w7u]], [[5w92|5w92]], [[5w9g|5w9g]], [[5wf3|5wf3]], [[5wa6|5wa6]], [[5wa7|5wa7]], [[5web|5web]], [[5wap|5wap]], [[5wb3|5wb3]], [[5wdw|5wdw]], [[5wcs|5wcs]], [[5wct|5wct]], [[5wdn|5wdn]], [[5we7|5we7]], [[5wdc|5wdc]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5w3i|5w3i]], [[5w44|5w44]], [[5wef|5wef]], [[5wei|5wei]], [[5we9|5we9]], [[5w73|5w73]], [[5w7u|5w7u]], [[5w92|5w92]], [[5w9g|5w9g]], [[5wf3|5wf3]], [[5wa6|5wa6]], [[5wa7|5wa7]], [[5web|5web]], [[5wap|5wap]], [[5wb3|5wb3]], [[5wdw|5wdw]], [[5wcs|5wcs]], [[5wct|5wct]], [[5wdn|5wdn]], [[5we7|5we7]], [[5wdc|5wdc]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=641501 I09A0])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wfm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wfm OCA], [http://pdbe.org/5wfm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wfm RCSB], [http://www.ebi.ac.uk/pdbsum/5wfm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wfm ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wfm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wfm OCA], [http://pdbe.org/5wfm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wfm RCSB], [http://www.ebi.ac.uk/pdbsum/5wfm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wfm ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| Line 17: | Line 18: | ||
</div> | </div> | ||
<div class="pdbe-citations 5wfm" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5wfm" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[RNA polymerase|RNA polymerase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: I09a0]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Kumar, G]] | [[Category: Kumar, G]] | ||
[[Category: White, S W]] | [[Category: White, S W]] | ||
Revision as of 17:35, 11 December 2019
Crystal structure of the influenza virus PA endonuclease (E119D mutant) in complex with inhibitor 10e (SRI-30024)
| |||||||||||
