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6u8l

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<StructureSection load='6u8l' size='340' side='right'caption='[[6u8l]], [[Resolution|resolution]] 1.57&Aring;' scene=''>
<StructureSection load='6u8l' size='340' side='right'caption='[[6u8l]], [[Resolution|resolution]] 1.57&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6u8l]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6U8L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6U8L FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6u8l]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6U8L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6U8L FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=Q1P:3-{[(5-bromo-2-hydroxyphenyl)sulfonyl]amino}-5-cyclopropyl-6-fluoro-2-hydroxybenzoic+acid'>Q1P</scene>, <scene name='pdbligand=Q1S:N-[2-(4-methylpiperazin-1-yl)-5-nitrophenyl]isoquinolin-1-amine'>Q1S</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=Q1P:3-{[(5-bromo-2-hydroxyphenyl)sulfonyl]amino}-5-cyclopropyl-6-fluoro-2-hydroxybenzoic+acid'>Q1P</scene>, <scene name='pdbligand=Q1S:N-[2-(4-methylpiperazin-1-yl)-5-nitrophenyl]isoquinolin-1-amine'>Q1S</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">WDR5, BIG3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6u8l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6u8l OCA], [http://pdbe.org/6u8l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6u8l RCSB], [http://www.ebi.ac.uk/pdbsum/6u8l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6u8l ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6u8l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6u8l OCA], [http://pdbe.org/6u8l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6u8l RCSB], [http://www.ebi.ac.uk/pdbsum/6u8l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6u8l ProSAT]</span></td></tr>
</table>
</table>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Wang, F]]
[[Category: Wang, F]]

Revision as of 13:19, 18 December 2019

Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction

PDB ID 6u8l

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