This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5dgw
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal Structure of HIV-1 Protease Inhibitor GRL-105-11A Containing Substituted fused-Tetrahydropyranyl Tetrahydrofuran as P2-Ligand== | ==Crystal Structure of HIV-1 Protease Inhibitor GRL-105-11A Containing Substituted fused-Tetrahydropyranyl Tetrahydrofuran as P2-Ligand== | ||
| - | <StructureSection load='5dgw' size='340' side='right' caption='[[5dgw]], [[Resolution|resolution]] 1.62Å' scene=''> | + | <StructureSection load='5dgw' size='340' side='right'caption='[[5dgw]], [[Resolution|resolution]] 1.62Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5dgw]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DGW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DGW FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5dgw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DGW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DGW FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5B5:(3R,3AS,4S,7AS)-3-(ETHYLAMINO)HEXAHYDRO-4H-FURO[2,3-B]PYRAN-4-YL+[(2S,3R)-3-HYDROXY-4-{[(4-METHOXYPHENYL)SULFONYL](2-METHYLPROPYL)AMINO}-1-PHENYLBUTAN-2-YL]CARBAMATE'>5B5</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5B5:(3R,3AS,4S,7AS)-3-(ETHYLAMINO)HEXAHYDRO-4H-FURO[2,3-B]PYRAN-4-YL+[(2S,3R)-3-HYDROXY-4-{[(4-METHOXYPHENYL)SULFONYL](2-METHYLPROPYL)AMINO}-1-PHENYLBUTAN-2-YL]CARBAMATE'>5B5</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dgw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dgw OCA], [http://pdbe.org/5dgw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dgw RCSB], [http://www.ebi.ac.uk/pdbsum/5dgw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dgw ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dgw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dgw OCA], [http://pdbe.org/5dgw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dgw RCSB], [http://www.ebi.ac.uk/pdbsum/5dgw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dgw ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| Line 18: | Line 19: | ||
==See Also== | ==See Also== | ||
| - | *[[Immunodeficiency virus protease|Immunodeficiency virus protease]] | + | *[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Agniswamy, J]] | [[Category: Agniswamy, J]] | ||
[[Category: Wang, Y F]] | [[Category: Wang, Y F]] | ||
Revision as of 11:22, 25 December 2019
Crystal Structure of HIV-1 Protease Inhibitor GRL-105-11A Containing Substituted fused-Tetrahydropyranyl Tetrahydrofuran as P2-Ligand
| |||||||||||
