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5wkl
From Proteopedia
(Difference between revisions)
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==1.85 A resolution structure of MERS 3CL protease in complex with piperidine-based peptidomimetic inhibitor 17== | ==1.85 A resolution structure of MERS 3CL protease in complex with piperidine-based peptidomimetic inhibitor 17== | ||
| - | <StructureSection load='5wkl' size='340' side='right' caption='[[5wkl]], [[Resolution|resolution]] 1.85Å' scene=''> | + | <StructureSection load='5wkl' size='340' side='right'caption='[[5wkl]], [[Resolution|resolution]] 1.85Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5wkl]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WKL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WKL FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5wkl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mers Mers]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WKL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WKL FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AVY:(1R,2S)-2-{[N-({[4-benzyl-1-(tert-butoxycarbonyl)piperidin-4-yl]oxy}carbonyl)-L-leucyl]amino}-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic+acid'>AVY</scene>, <scene name='pdbligand=B3J:(1S,2S)-2-{[N-({[4-benzyl-1-(tert-butoxycarbonyl)piperidin-4-yl]oxy}carbonyl)-L-leucyl]amino}-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic+acid'>B3J</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AVY:(1R,2S)-2-{[N-({[4-benzyl-1-(tert-butoxycarbonyl)piperidin-4-yl]oxy}carbonyl)-L-leucyl]amino}-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic+acid'>AVY</scene>, <scene name='pdbligand=B3J:(1S,2S)-2-{[N-({[4-benzyl-1-(tert-butoxycarbonyl)piperidin-4-yl]oxy}carbonyl)-L-leucyl]amino}-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic+acid'>B3J</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">orf1a ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1335626 MERS])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wkl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wkl OCA], [http://pdbe.org/5wkl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wkl RCSB], [http://www.ebi.ac.uk/pdbsum/5wkl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wkl ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wkl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wkl OCA], [http://pdbe.org/5wkl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wkl RCSB], [http://www.ebi.ac.uk/pdbsum/5wkl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wkl ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mers]] | ||
[[Category: Battaile, K P]] | [[Category: Battaile, K P]] | ||
[[Category: Chang, K O]] | [[Category: Chang, K O]] | ||
Revision as of 09:55, 1 January 2020
1.85 A resolution structure of MERS 3CL protease in complex with piperidine-based peptidomimetic inhibitor 17
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