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EibD

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== Crystal structure of an immunoglobulin-binding fragment of the trimeric autotransporter adhesin (TAA) EibD ==
== Crystal structure of an immunoglobulin-binding fragment of the trimeric autotransporter adhesin (TAA) EibD ==
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<StructureSection load='2xqh' size='350' side='right' caption='Crystal structure of an immunoglobulin-binding fragment of the trimeric autotransporter adhesin (TAA) EibD (PDB entry [[2xqh]])' scene='<scene name='EibD/2xqh/1'></scene>'>
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<StructureSection load='2xqh' size='350' side='right' caption='Crystal structure of an immunoglobulin-binding fragment of the trimeric autotransporter adhesin (TAA) EibD (PDB entry [[2xqh]])' scene='EibD/2xqh/1'>
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{{ABSTRACT_PUBMED_21742268}}
{{ABSTRACT_PUBMED_21742268}}
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== About this Structure ==
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== Structure Features ==
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[[2xqh]] is a single chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XQH OCA]. The biological assembly consists of three copies of the monomer <scene name='EibD/2xqh_biological_assembly/1'>Biological Assembly</scene>.
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Space Group: H 3 (48.950x48.950x409.600, 90.00x90.00x120.00) <br>
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Resolution limit: 1.99 Å <br>
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R/R free: 0.1585/0.1855 <br>
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XQH OCA].<br>
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<scene name='EibD/2xqh/1'>Asymmetric unit</scene> contains a single polypeptide chain. The <scene name='EibD/2xqh_ba/3'>biological assembly</scene> consists of three copies of the monomer related by a <scene name='EibD/2xqh_ba/11'>three fold axis</scene>.
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There are five distinct domains:
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<ul>
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<li>YadA-like <scene name='EibD/2xqh_ba/5'> β-roll</scene> domain;
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<li><scene name='EibD/2xqh_ba/6'>neck</scene> domain;
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<li><scene name='EibD/2xqh_ba/7'>right handed</scene> coiled-coil domain;
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<li><scene name='EibD/2xqh_ba/8'>mini β-sheet</scene> domain;
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<li><scene name='EibD/2xqh_ba/9'>left handed</scene> coiled-coil domain;
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</ul>
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Coiled-coil features:
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<ul>
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<li> cavities
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<li> chloride coordination by <scene name='EibD/2xqh_ba/12'>Thr</scene> and <scene name='EibD/2xqh_ba/13'>Asn</scene> residues.
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</ul>
== General information ==
== General information ==

Current revision

Crystal structure of an immunoglobulin-binding fragment of the trimeric autotransporter adhesin (TAA) EibD

Crystal structure of an immunoglobulin-binding fragment of the trimeric autotransporter adhesin (TAA) EibD (PDB entry 2xqh)

Drag the structure with the mouse to rotate

Primery reference

  • Leo JC, Lyskowski A, Hattula K, Hartmann MD, Schwarz H, Butcher SJ, Linke D, Lupas AN, Goldman A. The Structure of E. coli IgG-Binding Protein D Suggests a General Model for Bending and Binding in Trimeric Autotransporter Adhesins. Structure. 2011 Jul 13;19(7):1021-30. PMID:21742268 doi:10.1016/j.str.2011.03.021
  1. September 2001 Molecule of the Month by David Goodsell http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_9

Proteopedia Page Contributors and Editors (what is this?)

Andrzej Lyskowski, Michal Harel

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