Semaphorin

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SEMA 1A
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**[[6qp9]] – DmSEMA 1A domain 1-2 – ''Drosophila melanogaster''<br />
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SEMA 2A
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**[[6qp7]] – DmSEMA 2A <br />
*Semaphorin 3
*Semaphorin 3

Revision as of 10:01, 21 January 2020

Glycosylated human semaphorin 7A (deeppink) complex with plexin-C1 (cyan) and Ca+2 ion (green), 3nvn

Drag the structure with the mouse to rotate

3D structures of semaphorin

21-January-2020 SEMA 1A

SEMA 2A

References

  1. ↑ Nakamura F, Kalb RG, Strittmatter SM. Molecular basis of semaphorin-mediated axon guidance. J Neurobiol. 2000 Aug;44(2):219-29. PMID:10934324
  2. ↑ Behar O, Golden JA, Mashimo H, Schoen FJ, Fishman MC. Semaphorin III is needed for normal patterning and growth of nerves, bones and heart. Nature. 1996 Oct 10;383(6600):525-8. PMID:8849723 doi:http://dx.doi.org/10.1038/383525a0
  3. ↑ Yang YH, Buhamrah A, Schneider A, Lin YL, Zhou H, Bugshan A, Basile JR. Semaphorin 4D Promotes Skeletal Metastasis in Breast Cancer. PLoS One. 2016 Feb 24;11(2):e0150151. doi: 10.1371/journal.pone.0150151., eCollection 2016. PMID:26910109 doi:http://dx.doi.org/10.1371/journal.pone.0150151
  4. ↑ Pasterkamp RJ, Peschon JJ, Spriggs MK, Kolodkin AL. Semaphorin 7A promotes axon outgrowth through integrins and MAPKs. Nature. 2003 Jul 24;424(6947):398-405. PMID:12879062 doi:http://dx.doi.org/10.1038/nature01790
  5. ↑ Pasterkamp RJ, Giger RJ. Semaphorin function in neural plasticity and disease. Curr Opin Neurobiol. 2009 Jun;19(3):263-74. doi: 10.1016/j.conb.2009.06.001. Epub, 2009 Jun 21. PMID:19541473 doi:http://dx.doi.org/10.1016/j.conb.2009.06.001
  6. ↑ Vadasz Z, Toubi E. Semaphorin 3A - a marker for disease activity and a potential putative disease-modifying treatment in systemic lupus erythematosus. Lupus. 2012 Oct;21(12):1266-70. Epub 2012 Aug 8. PMID:22875653 doi:http://dx.doi.org/10.1177/0961203312456753
  7. ↑ Liu H, Juo ZS, Shim AH, Focia PJ, Chen X, Garcia KC, He X. Structural basis of semaphorin-plexin recognition and viral mimicry from Sema7A and A39R complexes with PlexinC1. Cell. 2010 Sep 3;142(5):749-61. Epub 2010 Aug 19. PMID:20727575 doi:10.1016/j.cell.2010.07.040

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