This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6tp4
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='6tp4' size='340' side='right'caption='[[6tp4]], [[Resolution|resolution]] 3.01Å' scene=''> | <StructureSection load='6tp4' size='340' side='right'caption='[[6tp4]], [[Resolution|resolution]] 3.01Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6tp4]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TP4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TP4 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6tp4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TP4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TP4 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NRZ:(2~{S})-~{N}-(3,5-dimethylphenyl)-1-(4-methoxyphenyl)sulfonyl-pyrrolidine-2-carboxamide'>NRZ</scene>, <scene name='pdbligand=PGW:(1R)-2-{[(S)-{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(HEXADECANOYLOXY)METHYL]ETHYL+(9Z)-OCTADEC-9-ENOATE'>PGW</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SOG:2-HYDROXYMETHYL-6-OCTYLSULFANYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL'>SOG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NRZ:(2~{S})-~{N}-(3,5-dimethylphenyl)-1-(4-methoxyphenyl)sulfonyl-pyrrolidine-2-carboxamide'>NRZ</scene>, <scene name='pdbligand=PGW:(1R)-2-{[(S)-{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(HEXADECANOYLOXY)METHYL]ETHYL+(9Z)-OCTADEC-9-ENOATE'>PGW</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SOG:2-HYDROXYMETHYL-6-OCTYLSULFANYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL'>SOG</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6to7|6to7]], [[6tod|6tod]], [[6tos|6tos]], [[6tot|6tot]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6to7|6to7]], [[6tod|6tod]], [[6tos|6tos]], [[6tot|6tot]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HCRTR1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6tp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tp4 OCA], [http://pdbe.org/6tp4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tp4 RCSB], [http://www.ebi.ac.uk/pdbsum/6tp4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tp4 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6tp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tp4 OCA], [http://pdbe.org/6tp4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tp4 RCSB], [http://www.ebi.ac.uk/pdbsum/6tp4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tp4 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| Line 23: | Line 24: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Ali, A]] | [[Category: Ali, A]] | ||
Revision as of 16:23, 29 January 2020
Crystal structure of the Orexin-1 receptor in complex with ACT-462206
| |||||||||||
Categories: Human | Large Structures | Ali, A | Bennett, K A | Brown, J D | Bucknell, S J | Christopher, J A | Congreve, M | Cooke, R M | Cseke, G | Dore, A S | Errey, J C | Graaf, C de | Jazayeri, A | Marshall, F H | Mason, J S | Mould, R | Patel, J C | Rappas, M | Tehan, B G | Weir, M | Gpcr | Membrane protein
