Transcription initiation factor
From Proteopedia
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</StructureSection> | </StructureSection> | ||
| - | ==3D structures of transcription initiation factors== | ||
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| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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| - | *TFIIA | ||
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| - | **[[5m4s]] – hTFIIA – human<br /> | ||
| - | **[[6mzm]] – hTFIIA+TFIID + TBP + DNA – Cryo EM<br /> | ||
| - | **[[1nvp]] – hTFIIA + TBP + DNA <br /> | ||
| - | **[[5fur]] – hTFIIA + hTFIIF + TBP + DNA - CryoEM<br /> | ||
| - | **[[1ytf]], [[1nh2]], [[1rm1]] – yTFIIA + TBP + DNA – yeast<br /> | ||
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| - | *TFIIB | ||
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| - | **[[1tfb]] – hTFIIB - NMR<BR /> | ||
| - | **[[1dl6]] - hTFIIB N terminal – NMR<br /> | ||
| - | **[[5wh1]] - hTFIIB C terminal <br /> | ||
| - | **[[1rly]] - hTFIIB Zn ribbon domain + Zn – NMR<br /> | ||
| - | **[[1ro4]] - hTFIIB Zn ribbon domain – NMR<br /> | ||
| - | **[[1ais]], [[1d3u]] - TFIIB C terminal + TBP + DNA – ''Pyrococcus woesei''<br /> | ||
| - | **[[1pft]] – TFIIB N terminal – ''Pyrococcus furiosus'' – NMR<BR /> | ||
| - | **[[5o9j]], [[5o9i]] - TFIIB – ''Methanocaldococcus jannaschii'' <br /> | ||
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| - | *TFIIA+TFIIB | ||
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| - | **[[6o9l]] – hTFIIA+TFIIB in RNA polymerase II – Cryo EM<br /> | ||
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| - | *TFIIIB | ||
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| - | **[[5n9g]] – hTFIIIB + TBP + DNA<br /> | ||
| - | **[[6f44]], [[6f42]], [[6f41]], [[6f40]], [[6eu0]], [[6cnf]], [[6cnd]], [[6cnc]], [[6cnb]] – yTFIIIB + RNA polymerase III – Cryo EM<br /> | ||
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| - | *TFIID | ||
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| - | **[[1bh8]] – hTFIID<BR /> | ||
| - | **[[1eqf]] – hTFIID subunit 1<br /> | ||
| - | **[[6fic]] – hTFIID subunit 1 + inhibitor<br /> | ||
| - | **[[3uv5]] – hTFIID subunit 1 bromodomain 1-2<br /> | ||
| - | **[[3uv4]] – hTFIID subunit 1 bromodomain 2<br /> | ||
| - | **[[6bqd]] – hTFIID subunit 1 bromodomain 2 + inhibitor <br /> | ||
| - | **[[3aad]] – hTFIID subunit 1 bromodomain 1-2 + histone chaperone ASF1A<br /> | ||
| - | **[[5mg2]] – hTFIID subunit 1 bromodomain 2 + inhibitor<br /> | ||
| - | **[[4yym]], [[4yyn]] – hTFIID subunit 1 bromodomain 2 + histone peptide<br /> | ||
| - | **[[5c13]], [[5wxg]], [[5mxy]] – hTFIID subunit 3 PHD finger + histone peptide<br /> | ||
| - | **[[5wxh]] – hTFIID subunit 3 PHD finger + histone peptide<br /> | ||
| - | **[[5i1q]], [[5i29]] – hTFIID subunit 1 bromodomain 2 + pyrrolopyridone<br /> | ||
| - | **[[5eg2]] - hTFIID subunit 10 + SETD7 + SAH<br /> | ||
| - | **[[4wv4]] - hTFIID subunits 8+10 <br /> | ||
| - | **[[4grw]] - hTFIID subunits 1+7 <br /> | ||
| - | **[[6f39]] - hTFIID subunits 5+6+9 <br /> | ||
| - | **[[6mzl]] - hTFIID subunits 1-13 + TBP – Cryo EM<br /> | ||
| - | **[[6mzd]] - hTFIID subunits 1,3-6,9-13 + TBP – Cryo EM<br /> | ||
| - | **[[6mzc]] - hTFIID subunits 2,4-6,8-12 – Cryo EM<br /> | ||
| - | **[[1bh9]] – hTFIID + PCMBS<BR /> | ||
| - | **[[6df7]], [[6df4]] – TFIID subunit 1 bromodomain 2 + inhibitor - rabbit<br /> | ||
| - | **[[1tba]] – TFIID – ''Drosophila melanogaster'' - NMR<BR /> | ||
| - | **[[1qn3]], [[1qn4]], [[1qn5]], [[1qn6]], [[1qn7]], [[1qn8]], [[1qn9]], [[1qna]], [[1qnb]], [[1qnc]], [[1qne]] – TFIID + DNA – ''Arabidopsis thaliana''<br /> | ||
| - | **[[4oy2]] - yTFIID subunits 1+7 <br /> | ||
| - | **[[6mip]] - yTFIID subunits 14 <br /> | ||
| - | **[[5iok]], [[5o7e]], [[6miq]], [[6mio]], [[6min]] – yTFIID subunit 14 + histone peptide<br /> | ||
| - | **[[6t9j]] - yTFIID subunit 12 + Spt20 + transcription-associated protein – Cryo EM <br /> | ||
| - | **[[6t9k]], [[6t9i]] - yTFIID in SAGA complex – Cryo EM <br /> | ||
| - | **[[6tbm]], [[6tb4]] - TFIID in SAGA complex – ''Komagataella phaffii'' – Cryo EM <br /> | ||
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| - | *TFIIE | ||
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| - | **[[5gpy]] - hTFIIE subunits α+β<br /> | ||
| - | **[[1vd4]] - hTFIIE Zn finger domain – NMR<br /> | ||
| - | **[[2rnq]] – hTFIIE C terminal - NMR<br /> | ||
| - | **[[2rnr]] – hTFIIE C terminal + TFIIH PH domain- NMR<br /> | ||
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| - | *TFIIF | ||
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| - | **[[1f3u]] – hTFIIF<br /> | ||
| - | **[[1nha]] – hTFIIF C terminal - NMR<br /> | ||
| - | **[[1i27]] – hTFIIF C terminal (mutant)<br /> | ||
| - | **[[1j2x]] – hTFIIF C terminal + RNA polymerase CTD phosphatase peptide<br /> | ||
| - | **[[1onv]] – hTFIIF C terminal + serine phosphatase peptide - NMR<br /> | ||
| - | **[[2k7l]] – hTFIIF C terminal + FCP1 peptide - NMR<br /> | ||
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| - | *TF in RNA polymerase II | ||
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| - | **[[5iy6]], [[5iy7]], [[5iy8]], [[5iy9]], [[5iya]], [[5iyb]], [[5iyc]], [[5iyd]] – hTFIIA + hTFIIB + hTFIIE + hTFIIF + hTFIIH + DNA – Cryo EM<br /> | ||
| - | **[[5fyw]] – yTFIIA + yTFIIE + yTFIIF + DNA <br /> | ||
| - | **[[5fz5]], [[6gym]], [[6gyl]] – yTFIIA + yTFIIE + yTFIIF + DNA – Cryo EM<br /> | ||
| - | **[[6gyk]] – yTFIIA + yTFIIB + yTFIIF + DNA – Cryo EM<br /> | ||
| - | **[[4v1o]], [[4v1n]] – yTFIIB + yTFIIF – Cryo EM<br /> | ||
| - | **[[3k1f]], [[3k7a]], [[4bbr]], [[4bbs]] – yTFIIB <br /> | ||
| - | **[[5fmf]], [[5sva]], [[5oqj]], [[5oqm]] – yTFIIA + yTFIIB + yTFIIE + yTFIIF + yTFIIH + DNA – Cryo EM<br /> | ||
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| - | *TF RRN in RNA polymerase I | ||
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| - | **[[5o7x]] – yTF RRN6+RRN7+RRN11 <br /> | ||
| - | **[[5g5l]] – yTF RRN3 in RNA polymerase I<br /> | ||
| - | **[[6rrd]], [[6rqt]] – yTF RRN3 in RNA polymerase I – Cryo EM<br /> | ||
| - | **[[6ruo]] – yTF RRN3+RRN6+RRN11 in RNA polymerase I – Cryo EM<br /> | ||
| - | **[[5w66]], [[5w65]], [[5w64]], [[5w5y]], [[5oa1]] – yTF RRN6+RRN7+RRN11 in RNA polymerase I – Cryo EM<br /> | ||
| - | **[[6rwe]], [[6rui]], [[6rql]], [[6rqh]], [[5n61]], [[5n60]], [[5n5z]], [[5n5y]] – yTF RRN3+RRN6+RRN7+RRN11 in RNA polymerase I – Cryo EM<br /> | ||
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| - | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
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References
- ↑ Roeder RG. The role of general initiation factors in transcription by RNA polymerase II. Trends Biochem Sci. 1996 Sep;21(9):327-35. PMID:8870495
- ↑ Kuhlman TC, Cho H, Reinberg D, Hernandez N. The general transcription factors IIA, IIB, IIF, and IIE are required for RNA polymerase II transcription from the human U1 small nuclear RNA promoter. Mol Cell Biol. 1999 Mar;19(3):2130-41. PMID:10022900
- ↑ Ha I, Lane WS, Reinberg D. Cloning of a human gene encoding the general transcription initiation factor IIB. Nature. 1991 Aug 22;352(6337):689-95. PMID:1876184 doi:http://dx.doi.org/10.1038/352689a0
- ↑ Kassavetis GA, Geiduschek EP. Transcription factor TFIIIB and transcription by RNA polymerase III. Biochem Soc Trans. 2006 Dec;34(Pt 6):1082-7. doi: 10.1042/BST0341082. PMID:17073756 doi:http://dx.doi.org/10.1042/BST0341082
- ↑ Peterson MG, Inostroza J, Maxon ME, Flores O, Admon A, Reinberg D, Tjian R. Structure and functional properties of human general transcription factor IIE. Nature. 1991 Dec 5;354(6352):369-73. PMID:1956398 doi:http://dx.doi.org/10.1038/354369a0
- ↑ Yamamoto RT, Nogi Y, Dodd JA, Nomura M. RRN3 gene of Saccharomyces cerevisiae encodes an essential RNA polymerase I transcription factor which interacts with the polymerase independently of DNA template. EMBO J. 1996 Aug 1;15(15):3964-73. PMID:8670901
