6u5z
From Proteopedia
(Difference between revisions)
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==Cryo-EM structure of E. coli LonA S679A== | ==Cryo-EM structure of E. coli LonA S679A== | ||
| - | < | + | <SX load='6u5z' size='340' side='right' viewer='molstar' caption='[[6u5z]], [[Resolution|resolution]] 3.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6u5z]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6U5Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6U5Z FirstGlance]. <br> | <table><tr><td colspan='2'>[[6u5z]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6U5Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6U5Z FirstGlance]. <br> | ||
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[[http://www.uniprot.org/uniprot/C3TLS2_ECOLX C3TLS2_ECOLX]] ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. Endogenous substrates include the regulatory proteins RcsA and SulA, the transcriptional activator SoxS, and UmuD. Its overproduction specifically inhibits translation through at least two different pathways, one of them being the YoeB-YefM toxin-antitoxin system.[HAMAP-Rule:MF_01973] | [[http://www.uniprot.org/uniprot/C3TLS2_ECOLX C3TLS2_ECOLX]] ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. Endogenous substrates include the regulatory proteins RcsA and SulA, the transcriptional activator SoxS, and UmuD. Its overproduction specifically inhibits translation through at least two different pathways, one of them being the YoeB-YefM toxin-antitoxin system.[HAMAP-Rule:MF_01973] | ||
__TOC__ | __TOC__ | ||
| - | </ | + | </SX> |
[[Category: Endopeptidase La]] | [[Category: Endopeptidase La]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
Revision as of 01:07, 7 March 2020
Cryo-EM structure of E. coli LonA S679A
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