Uridylate kinase

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Line 23: Line 23:
*Uridylate kinase complex with nucleotides
*Uridylate kinase complex with nucleotides
 +
**[[1uky]] – yUK + ADP – yeast<br />
**[[1ukz]] – yUK + AMP + ADP<br />
**[[1ukz]] – yUK + AMP + ADP<br />
**[[2bne]] – EcUK (mutant) + UMP – ''Escherichia coli''<br />
**[[2bne]] – EcUK (mutant) + UMP – ''Escherichia coli''<br />
Line 35: Line 36:
**[[2j4l]] - SsUK + UTP<br />
**[[2j4l]] - SsUK + UTP<br />
**[[2jjx]] - UK + ATP + Mg – ''Bacillus anthracis''<br />
**[[2jjx]] - UK + ATP + Mg – ''Bacillus anthracis''<br />
-
**[[1uky]] – yUK + ADP – yeast<br />
 
**[[3ek5]] - XcUK + GTP <br />
**[[3ek5]] - XcUK + GTP <br />
**[[3nwy]] – UK + UTP + GTP – ''Mycobacterium tuberculosis''<br />
**[[3nwy]] – UK + UTP + GTP – ''Mycobacterium tuberculosis''<br />

Revision as of 10:34, 23 March 2020

Uridylate kinase hexamer complex with ligand UMP, Cd+ (gold) and Mg+2 (green) ions 2j4k

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3D structures of uridylate kinase

Updated on 23-March-2020

References

  1. Yan H, Tsai MD. Nucleoside monophosphate kinases: structure, mechanism, and substrate specificity. Adv Enzymol Relat Areas Mol Biol. 1999;73:103-34, x. PMID:10218107
  2. Jensen KS, Johansson E, Jensen KF. Structural and enzymatic investigation of the Sulfolobus solfataricus uridylate kinase shows competitive UTP inhibition and the lack of GTP stimulation. Biochemistry. 2007 Mar 13;46(10):2745-57. Epub 2007 Feb 13. PMID:17297917 doi:10.1021/bi0618159

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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