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6m02
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==cryo-EM structure of human Pannexin 1 channel== | |
| - | + | <StructureSection load='6m02' size='340' side='right'caption='[[6m02]], [[Resolution|resolution]] 3.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6m02]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M02 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6M02 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PANX1, MRS1, UNQ2529/PRO6028 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6m02 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m02 OCA], [http://pdbe.org/6m02 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6m02 RCSB], [http://www.ebi.ac.uk/pdbsum/6m02 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6m02 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PANX1_HUMAN PANX1_HUMAN]] Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis.<ref>PMID:16908669</ref> <ref>PMID:20829356</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Jilin, Z]] | ||
| + | [[Category: Lei, W]] | ||
| + | [[Category: Lili, D]] | ||
| + | [[Category: Ronggui, Q]] | ||
| + | [[Category: Shujia, Z]] | ||
| + | [[Category: Xuekui, Y]] | ||
| + | [[Category: Ion channel]] | ||
| + | [[Category: Membrane protein]] | ||
| + | [[Category: Molecular penetrate]] | ||
Current revision
cryo-EM structure of human Pannexin 1 channel
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Categories: Human | Large Structures | Jilin, Z | Lei, W | Lili, D | Ronggui, Q | Shujia, Z | Xuekui, Y | Ion channel | Membrane protein | Molecular penetrate
