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6et5

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Reaction centre light harvesting complex 1 from Blc. virids

6et5, resolution 3.00Å

Structural highlights

6et5 is a 54 chain structure with sequence from Blastochloris viridis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Experimental data:	Check to display Experimental Data
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[LHB_BLAVI] Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers. [RCEH_BLAVI] The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis. [CYCR_BLAVI] The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor.^[1] [RCEM_BLAVI] The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis. [LHG_BLAVI] One of the components of the bacteriochlorophyll-protein complex in the chromatophore membrane. [RCEL_BLAVI] The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis. [LHA_BLAVI] Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.

Publication Abstract from PubMed

The light-harvesting 1-reaction centre (LH1-RC) complex is a key functional component of bacterial photosynthesis. Here we present a 2.9 A resolution cryo-electron microscopy structure of the bacteriochlorophyll b-based LH1-RC complex from Blastochloris viridis that reveals the structural basis for absorption of infrared light and the molecular mechanism of quinone migration across the LH1 complex. The triple-ring LH1 complex comprises a circular array of 17 beta-polypeptides sandwiched between 17 alpha- and 16 gamma-polypeptides. Tight packing of the gamma-apoproteins between beta-polypeptides collectively interlocks and stabilizes the LH1 structure; this, together with the short Mg-Mg distances of bacteriochlorophyll b pairs, contributes to the large redshift of bacteriochlorophyll b absorption. The 'missing' 17th gamma-polypeptide creates a pore in the LH1 ring, and an adjacent binding pocket provides a folding template for a quinone, Q P, which adopts a compact, export-ready conformation before passage through the pore and eventual diffusion to the cytochrome bc 1 complex.

Cryo-EM structure of the Blastochloris viridis LH1-RC complex at 2.9 A.,Qian P, Siebert CA, Wang P, Canniffe DP, Hunter CN Nature. 2018 Apr;556(7700):203-208. doi: 10.1038/s41586-018-0014-5. Epub 2018 Apr, 4. PMID:29618818^[2]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Chen IP, Mathis P, Koepke J, Michel H. Uphill electron transfer in the tetraheme cytochrome subunit of the Rhodopseudomonas viridis photosynthetic reaction center: evidence from site-directed mutagenesis. Biochemistry. 2000 Apr 4;39(13):3592-602. PMID:10736158
↑ Qian P, Siebert CA, Wang P, Canniffe DP, Hunter CN. Cryo-EM structure of the Blastochloris viridis LH1-RC complex at 2.9 A. Nature. 2018 Apr;556(7700):203-208. doi: 10.1038/s41586-018-0014-5. Epub 2018 Apr, 4. PMID:29618818 doi:http://dx.doi.org/10.1038/s41586-018-0014-5

1 Structural highlights
2 Function
3 Publication Abstract from PubMed
4 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6et5"

@@ Line 1: / Line 1: @@
-==Reaction centre light harvesting complex 1 from Blc. viridian==
+==Reaction centre light harvesting complex 1 from Blc. virids==
-<StructureSection load='6et5' size='340' side='right' caption='[[6et5]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
+<SX load='6et5' size='340' side='right' viewer='molstar' caption='[[6et5]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[6et5]] is a 54 chain structure with sequence from [http://en.wikipedia.org/wiki/Blastochloris_viridis Blastochloris viridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ET5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ET5 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6et5]] is a 54 chain structure with sequence from [http://en.wikipedia.org/wiki/Blastochloris_viridis Blastochloris viridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ET5 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6ET5 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BCB:BACTERIOCHLOROPHYLL+B'>BCB</scene>, <scene name='pdbligand=BPB:BACTERIOPHEOPHYTIN+B'>BPB</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene>, <scene name='pdbligand=MQ9:MENAQUINONE-9'>MQ9</scene>, <scene name='pdbligand=NS0:all-trans-1,2-dihydroneurosporene'>NS0</scene>, <scene name='pdbligand=NS5:15-CIS-1,2-DIHYDRONEUROSPORENE'>NS5</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UQ9:UBIQUINONE-9'>UQ9</scene></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BCB:BACTERIOCHLOROPHYLL+B'>BCB</scene>, <scene name='pdbligand=BPB:BACTERIOPHEOPHYTIN+B'>BPB</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene>, <scene name='pdbligand=MQ9:MENAQUINONE-9'>MQ9</scene>, <scene name='pdbligand=NS0:all-trans-1,2-dihydroneurosporene'>NS0</scene>, <scene name='pdbligand=NS5:15-CIS-1,2-DIHYDRONEUROSPORENE'>NS5</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UQ9:UBIQUINONE-9'>UQ9</scene></td></tr>
 <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=FME:N-FORMYLMETHIONINE'>FME</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6et5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6et5 OCA], [http://pdbe.org/6et5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6et5 RCSB], [http://www.ebi.ac.uk/pdbsum/6et5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6et5 ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6et5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6et5 OCA], [http://pdbe.org/6et5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6et5 RCSB], [http://www.ebi.ac.uk/pdbsum/6et5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6et5 ProSAT]</span></td></tr>
 </table>
 == Function ==
@@ Line 22: / Line 22: @@
 <references/>
 __TOC__
-</StructureSection>
+</SX>
 [[Category: Blastochloris viridis]]
+[[Category: Large Structures]]
 [[Category: Canniffe, D P]]
 [[Category: Hunter, C N]]

6et5

From Proteopedia

Current revision

Reaction centre light harvesting complex 1 from Blc. virids

Structural highlights

Function

Publication Abstract from PubMed

References

Contents

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