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6feq

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==Structure of inhibitor-bound ABCG2==
==Structure of inhibitor-bound ABCG2==
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<StructureSection load='6feq' size='340' side='right' caption='[[6feq]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
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<SX load='6feq' size='340' side='right' viewer='molstar' caption='[[6feq]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6feq]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FEQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FEQ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6feq]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FEQ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6FEQ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D6T:~{N}-[5-[1-[4-[2-[6-methoxy-7-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-3,4-dihydro-1~{H}-isoquinolin-2-yl]ethyl]phenyl]-1,2,3-triazol-4-yl]-2-propanoyl-phenyl]quinoline-2-carboxamide'>D6T</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D6T:~{N}-[5-[1-[4-[2-[6-methoxy-7-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-3,4-dihydro-1~{H}-isoquinolin-2-yl]ethyl]phenyl]-1,2,3-triazol-4-yl]-2-propanoyl-phenyl]quinoline-2-carboxamide'>D6T</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6feq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6feq OCA], [http://pdbe.org/6feq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6feq RCSB], [http://www.ebi.ac.uk/pdbsum/6feq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6feq ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ABCG2, ABCP, BCRP, BCRP1, MXR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6feq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6feq OCA], [http://pdbe.org/6feq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6feq RCSB], [http://www.ebi.ac.uk/pdbsum/6feq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6feq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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<references/>
<references/>
__TOC__
__TOC__
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</StructureSection>
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</SX>
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[[Category: Human]]
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[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
[[Category: Altmann, K H]]
[[Category: Altmann, K H]]
[[Category: Jackson, S M]]
[[Category: Jackson, S M]]

Current revision

Structure of inhibitor-bound ABCG2

6feq, resolution 3.60Å

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